Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 7/20 | 0.43 |
| ▸ | PPARA | Q07869 | 7/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | FPR2 | P25090 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4348494 | 0.92 | MGLL (0.40) | CYP1A2CYP2D6CYP2C19SMN1; SMN2MEN1 | |
| SCHEMBL4339384 | 0.90 | NPC1 (0.43) | CYP1A2CYP2D6CYP2C19SMN1; SMN2KMT2A | |
| SCHEMBL4333343 | 0.89 | PPARA (0.44) | SMN1; SMN2MEN1KMT2APPARGPPARA | |
| SCHEMBL4341155 | 0.89 | ALDH1A1 (0.48) | CYP1A2CYP2C19SMN1; SMN2MEN1KMT2A | |
| SCHEMBL4341908 | 0.89 | PPARG (0.47) | CYP1A2CYP2D6CYP2C19SMN1; SMN2MEN1 | |
| SCHEMBL4337170 | 0.88 | MMP1 (0.44) | CYP1A2CYP2D6CYP2C19SMN1; SMN2MEN1 | |
| SCHEMBL4337986 | 0.88 | SCD (0.42) | SMN1; SMN2MEN1KMT2APPARGPPARA | |
| SCHEMBL4488496 | 0.87 | PPARA (0.41) | CYP1A2CYP2C19SMN1; SMN2MEN1KMT2A | |
| SCHEMBL4331640 | 0.87 | PPARG (0.42) | CYP1A2CYP2D6CYP2C19SMN1; SMN2MEN1 | |
| SCHEMBL4327189 | 0.86 | PPARG (0.48) | CYP1A2CYP2D6CYP2C19SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7544835-B2 | Carboxylic acid derivative and salt thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |
| US-7544835-B2 | Carboxylic acid derivative and salt thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |
| US-7544835-B2 | Carboxylic acid derivative and salt thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |