SCHEMBL4342803

SCHEMBL4342803

CNc1nc(=O)[nH]cc1O

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MAT2A P31153 1/20 0.36
SHMT2 P34897 1/20 0.34
GAA P10253 1/20 0.33
DAO P14920 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1896687 0.78 MAT2A (0.37) MAT2A
SCHEMBL18325718 0.78 MAT2A (0.37) MAT2A
SCHEMBL3797103 0.76 MAT2A (0.36) MAT2A
SCHEMBL18610783 0.76 MAT2A (0.33) MAT2A
SCHEMBL18132314 0.73 KMT2A (0.35) MAT2A
SCHEMBL4512381 0.72
SCHEMBL8405047 0.71 LMNA (0.50) MAT2A
SCHEMBL31272046 0.69 PNP (0.38)
SCHEMBL65897 0.68
SCHEMBL15456758 0.68 ATAD2 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4409036-A1 A METHOD FOR DIAGNOSING AND PREDICTING PROGRESSION OF NEURODEGENERATIVE DISEASES OR DISORDERS Tivenix SA (CH) 2024-08-07 EP disclosed
WO-2023052640-A1 A METHOD FOR DIAGNOSING AND PREDICTING PROGRESSION OF NEURODEGENERATIVE DISEASES OR DISORDERS TIVENIX SA (CH) 2023-04-06 WO disclosed
EP-4143313-A2 METHOD FOR IDENTIFICATION AND RELATIVE QUANTIFICATION OF NUCLEIC ACID SEQUENCE, MUTATION, COPY NUMBER, OR METHYLATION CHANGES Cornell University (US) 2023-03-08 EP disclosed
WO-2022126938-A1 METHOD FOR DETECTING POLYNUCLEOTIDE VARIATIONS 广州市基准医疗有限责任公司 2022-06-23 WO disclosed
EP-3990657-A2 REAGENTS AND METHODS FOR THE ANALYSIS OF MICROPARTICLES CS Genetics Limited (GB) 2022-05-04 EP disclosed
EP-2013344-A2 ANTISENSE AGENTS COMBINING STRONGLY BOUND BASE - MODIFIED OLIGONUCLEOTIDE AND ARTIFICIAL NUCLEASE Baltic Technology Development, Ltd. (EE) 2009-01-14 EP disclosed
WO-2007125173-A2 ANTISENSE AGENTS COMBINING STRONGLY BOUND BASE - MODIFIED OLIGONUCLEOTIDE AND ARTIFICIAL NUCLEASE BALTIC TECHNOLOGY DEVELOPMENT, LTD. (EE) 2007-11-08 WO disclosed