Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 2/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MC4R | P32245 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | MC3R | P41968 | 1/20 | 0.33 |
| ▸ | SORD | Q00796 | 1/20 | 0.33 |
| ▸ | CCR9 | P51686 | 1/20 | 0.32 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29743114 | 0.77 | RECQL (0.39) | P4HTMKDM4EALDH1A1HSP90AA1NAPRT | |
| SCHEMBL5616510 | 0.72 | HTT (0.56) | P4HTMKDM4EALDH1A1MAOBTSHR | |
| SCHEMBL8470425 | 0.72 | P4HTM (0.37) | P4HTMKDM4EALDH1A1EGLN2SORD | |
| SCHEMBL718706 | 0.70 | SMN1; SMN2 (0.62) | BCHEMGLLKDM4EALDH1A1TLR9 | |
| SCHEMBL29760726 | 0.68 | SMN1; SMN2 (0.60) | BCHEMGLLKDM4EALDH1A1TLR9 | |
| SCHEMBL1713643 | 0.67 | MAOB (0.38) | P4HTMKDM4EALDH1A1HSP90AA1MAOB | |
| SCHEMBL5000576 | 0.67 | HSP90AA1 (0.40) | P4HTMKDM4EHSP90AA1NAPRTHCAR2 | |
| SCHEMBL20062935 | 0.67 | L3MBTL1 (0.46) | P4HTMKDM4EALDH1A1HSP90AA1SORD | |
| SCHEMBL9418762 | 0.67 | BCHE (0.55) | BCHEMGLLFAAHALDH1A1HSP90AA1 | |
| SCHEMBL7490482 | 0.65 | KDM4E (0.49) | KDM4EALDH1A1SORD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9845460-B2 | Treatment of pluripotent cells | JANSSEN BIOTECH, INC. (US) | 2017-12-19 | — | — | US | disclosed |
| US-20140080210-A1 | Treatment of Pluripotent Cells | JANSSEN BIOTECH, INC. (US) | 2014-03-20 | — | — | US | disclosed |
| US-8623648-B2 | Treatment of pluripotent cells | JANSSEN BIOTECH, INC. (US) | 2014-01-07 | — | — | US | disclosed |
| US-20090325293-A1 | TREATMENT OF PLURIPOTENT CELLS | JANSSEN BIOTECH, INC. | 2009-12-31 | — | — | US | disclosed |