Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 4/20 | 0.48 |
| ▸ | TTR | P02766 | 2/20 | 0.44 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | GGT1 | P19440 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MARK4 | Q96L34 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | BCHE | P06276 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL563959 | 0.84 | GAA (0.42) | SNCALRRK2KMT2AMEN1RAB9A | |
| SCHEMBL433232 | 0.82 | NOX1 (0.42) | SNCAKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL436033 | 0.80 | NOX1 (0.41) | SNCAKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL433635 | 0.79 | MAPT (0.39) | SNCAKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL435356 | 0.79 | NOX1 (0.35) | SNCAKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL434466 | 0.79 | MAPT (0.46) | SNCATTRLRRK2KMT2AMEN1 | |
| SCHEMBL434961 | 0.79 | NOX1 (0.46) | SNCAKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL434444 | 0.77 | NOX1 (0.36) | SNCAKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL433397 | 0.76 | MAPT (0.41) | SNCAKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL432486 | 0.76 | MEN1 (0.45) | SNCALRRK2KMT2AMEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11851685-B2 | Zwitterion buffer containing compositions and uses in electroanalytical devices and methods | ROCHE DIABETES CARE, INC. (US) | 2023-12-26 | — | — | US | claimed |
| EP-1867732-A1 | Reagents, methods and devices for detecting analytes | Bayer Corporation (US) | 2007-12-19 | — | — | EP | claimed |
| EP-1293574-B1 | Reagents, methods and devices for detecting analytes | BAYER CORP (US) | 2007-11-21 | — | — | EP | claimed |
| US-7163616-B2 | Reagents and methods for detecting analytes, and devices comprising reagents for detecting analytes | BAYER CORPORATION (US) | 2007-01-16 | — | — | US | claimed |
| US-20030094384-A1 | Reagents and methods for detecting analytes, and devices comprising reagents for detecting analytes | ASCENSIA DIABETES CARE HOLDINGS AG (CH) | 2003-05-22 | — | — | US | claimed |
| EP-1293574-A2 | Reagents, methods and devices for detecting analytes | Bayer Corporation (US) | 2003-03-19 | — | — | EP | claimed |
| EP-0747984-B1 | Mediators suitable for the electrochemical regeneration of NADH, NADPH or analogs thereof | BAYER AG (US) | 2002-08-14 | — | — | EP | claimed |
| EP-0747984-A2 | Mediators suitable for the electrochemical regeneration of NADH, NADPH or analogs thereof | Bayer Corporation (US) | 1996-12-11 | — | — | EP | claimed |
| US-5520786-A | ELECTRODE SURFACE HAS BEEN IMPARTED BY A MEDIATOR FUNCTION COMPRISING ONE OR MORE MEDIATOR COMPOUNDS SELECTED FROM SUBSTITUTED OR UNSUBSTITUTED 3-PHENYLIMINO-3H-PHENOTHIAZINES AND 3-PHENYLIMINO-3H-PHENOXAZINES | BAYER CORPORATION (US) | 1996-05-28 | — | — | US | claimed |
| JP-9169749-A | — | — | None | — | — | JP | disclosed |
| US-11851685-B2 | Zwitterion buffer containing compositions and uses in electroanalytical devices and methods | ROCHE DIABETES CARE, INC. (US) | 2023-12-26 | — | — | US | disclosed |
| US-20220275348-A1 | ZWITTERION BUFFER CONTAINING COMPOSITIONS AND USES IN ELECTROANALYTICAL DEVICES AND METHODS | ROCHE DIABETES CARE, INC. | 2022-09-01 | — | — | US | disclosed |
| EP-3388824-B1 | METHODS OF DETECTING HIGH ANTIOXIDANT LEVELS DURING ELECTROCHEMICAL MEASUREMENTS AND FAILSAFING AN ANALYTE CONCENTRATION THEREFROM AS WELL AS DEVICES AND SYSTEMS INCORPORTING THE SAME | ROCHE DIABETES CARE GMBH (DE) | 2021-04-14 | — | — | EP | disclosed |
| US-20190264181-A1 | ZWITTERION BUFFER CONTAINING COMPOSITIONS AND USES IN ELECTROANALYTICAL DEVICES AND METHODS | ROCHE DIAGNOSTICS OPERATIONS, INC. | 2019-08-29 | — | — | US | disclosed |
| US-7163616-B2 | Reagents and methods for detecting analytes, and devices comprising reagents for detecting analytes | BAYER CORPORATION (US) | 2007-01-16 | — | — | US | disclosed |
| US-20030094384-A1 | Reagents and methods for detecting analytes, and devices comprising reagents for detecting analytes | ASCENSIA DIABETES CARE HOLDINGS AG (CH) | 2003-05-22 | — | — | US | disclosed |
| EP-1293574-A2 | Reagents, methods and devices for detecting analytes | Bayer Corporation (US) | 2003-03-19 | — | — | EP | disclosed |
| JP-H09169749-A | PRODUCTION OF SUBSTITUTED 3-(PHENYLIMINO)-3H-PHENOTHIAZINES AND PHENOXAZINES | BAYER CORP | 1997-06-30 | — | — | JP | disclosed |
| EP-0775699-A1 | Method for the preparation of substituted 3-(phenylimino)-3H-phenothiazines and phenoxazines | Bayer Corporation (US) | 1997-05-28 | — | — | EP | disclosed |
| US-5631371-A | Method for the preparation of substituted 3-(phenylimino)-3H-phenothiazines and phenoxazines | BAYER CORPORATION (US) | 1997-05-20 | — | — | US | disclosed |