Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL405777 | 0.85 | MIF (0.33) | — | |
| SCHEMBL15237109 | 0.85 | PTGER4 (0.33) | PTGER4PTGER2 | |
| SCHEMBL437422 | 0.85 | PTGER4 (0.37) | PTGER4PTGER2 | |
| SCHEMBL439648 | 0.84 | PTGER4 (0.33) | PTGER4 | |
| Hydrochloric Acid SCHEMBL28753862 | 0.84 | PTGER4 (0.37) | PTGER4PTGER2 | |
| SCHEMBL13723232 | 0.84 | PTGER4 (0.34) | PTGER4PTGER2 | |
| SCHEMBL14960654 | 0.80 | ALDH1A1 (0.37) | PTGER4 | |
| SCHEMBL29563727 | 0.75 | ALDH1A1 (0.38) | PTGER4 | |
| SCHEMBL13732493 | 0.75 | TAS1R3 (0.40) | — | |
| SCHEMBL1308467 | 0.75 | KDM4E (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 109 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4103553-A1 | NEW PROCESS FOR THE SYNTHESIS OF 5-FLUORO-3- (DIFUOROMETHYL) -5-FLUORO-1-METHYL-1H-PYRAZOLE-4-CARBOXYLIC ACID DERIVATIVES AND THE FREE ACID THEREOF | Fujian Yongjing Technology Co., Ltd (CN) | 2022-12-21 | — | — | EP | disclosed |
| US-20220372000-A1 | New Process for the Synthesis of 5-Fluoro-3-(Difuoromethyl)-5-Fluoro-1-Methyl-1H-Pyrazole-4-Carboxylic Acid Derivatives and the Free Acid Thereof | Fujian Yongjing Technology Co.,Ltd (CN) | 2022-11-24 | — | — | US | disclosed |
| US-20220372000-A1 | New Process for the Synthesis of 5-Fluoro-3-(Difuoromethyl)-5-Fluoro-1-Methyl-1H-Pyrazole-4-Carboxylic Acid Derivatives and the Free Acid Thereof | Fujian Yongjing Technology Co.,Ltd (CN) | 2022-11-24 | — | — | US | disclosed |
| CN-114450269-A | Novel method for synthesizing 5-fluoro-3- (difluoromethyl) -5-fluoro-1-methyl-1H-pyrazole-4-carboxylic acid derivative and free acid thereof | 福建永晶科技股份有限公司 | 2022-05-06 | — | — | CN | disclosed |
| CN-114450269-A | Novel method for synthesizing 5-fluoro-3- (difluoromethyl) -5-fluoro-1-methyl-1H-pyrazole-4-carboxylic acid derivative and free acid thereof | 福建永晶科技股份有限公司 | 2022-05-06 | — | — | CN | disclosed |
| EP-3288923-B1 | METHOD FOR PREPARING 5-FLUORO-1H-PYRAZOLE-4-CARBONYL FLUORIDES | BAYER CROPSCIENCE AG (DE) | 2020-02-12 | — | — | EP | disclosed |
| EP-3000809-B1 | FUNGICIDE PYRAZOLE CARBOXAMIDES DERIVATIVES | BAYER IP GMBH (DE) | 2018-10-31 | — | — | EP | disclosed |
| US-20180118690-A1 | METHOD FOR PREPARING 5-FLUORO-1H-PYRAZOLE-4-CARBONYL FLUORIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-05-03 | — | — | US | disclosed |
| US-20180118690-A1 | METHOD FOR PREPARING 5-FLUORO-1H-PYRAZOLE-4-CARBONYL FLUORIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-05-03 | — | — | US | disclosed |
| US-9951023-B2 | Process for preparing 5-fluoro-1-alkyl-3-fluoroalkyl-1H-pyrazole-4-carbaldehyde | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-04-24 | — | — | US | disclosed |
| EP-2430000-A2 | FUNGICIDE PYRAZOLE CARBOXAMIDES DERIVATIVES | Bayer CropScience Aktiengesellschaft (DE) | 2012-03-21 | — | — | EP | disclosed |
| US-20120065164-A1 | FUNGICIDE PYRAZOLE CARBOXAMIDES DERIVATES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2012-03-15 | — | — | US | disclosed |
| WO-2011151370-A1 | N-[(HET)ARYLALKYL)] PYRAZOLE (THIO)CARBOXAMIDES AND THEIR HETEROSUBSTITUTED ANALOGUES | BAYER CROPSCIENCE AG (DE) | 2011-12-08 | — | — | WO | disclosed |
| WO-2011151369-A1 | N-[(HET)ARYLETHYL)] PYRAZOLE(THIO)CARBOXAMIDES AND THEIR HETEROSUBSTITUTED ANALOGUES | BAYER CROPSCIENCE AG (DE) | 2011-12-08 | — | — | WO | disclosed |
| WO-2011151383-A1 | O-CYCLOPROPYLCYCLOHEXYL-CARBOXANILIDES AND THEIR USE AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2011-12-08 | — | — | WO | disclosed |
| WO-2011151383-A1 | O-CYCLOPROPYLCYCLOHEXYL-CARBOXANILIDES AND THEIR USE AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2011-12-08 | — | — | WO | disclosed |
| US-20110288305-A1 | Process for the preparation of 5-Fluoro-1-alkyl-3-fluoroalkyl-1H-pyrazole-4-carbonyl Chlorides and Fluorides | BAYER CROPSCIENCE AG (DE) | 2011-11-24 | — | — | US | disclosed |
| US-20110288305-A1 | Process for the preparation of 5-Fluoro-1-alkyl-3-fluoroalkyl-1H-pyrazole-4-carbonyl Chlorides and Fluorides | BAYER CROPSCIENCE AG (DE) | 2011-11-24 | — | — | US | disclosed |
| WO-2010130767-A2 | FUNGICIDE PYRAZOLE CARBOXAMIDES DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2010-11-18 | — | — | WO | disclosed |
| EP-2251331-A1 | Fungicide pyrazole carboxamides derivatives | Bayer CropScience AG (DE) | 2010-11-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110288305-A1 | Process for the preparation of 5-Fluoro-1-alkyl-3-fluoroalkyl-1H-pyrazole-4-carbonyl Chlorides and Fluorides | AFF4, AFF1, FLI1 | PTGER4 4114/4885PTGER2 4849/4885 |
| US-20220372000-A1 | New Process for the Synthesis of 5-Fluoro-3-(Difuoromethyl)-5-Fluoro-1-Methyl-1H-Pyrazole-4-Carboxylic Acid Derivatives and the Free Acid Thereof | CYP2F1, FDPS, FIBP | PTGER4 1980/4885PTGER2 3446/4885 |
| US-20180118690-A1 | METHOD FOR PREPARING 5-FLUORO-1H-PYRAZOLE-4-CARBONYL FLUORIDES | AFF4, AFF1, KCNK5 | PTGER4 3739/4885PTGER2 4849/4885 |
| US-20120065164-A1 | FUNGICIDE PYRAZOLE CARBOXAMIDES DERIVATES | CASP5, CTRL, CBR3 | PTGER4 4061/4885PTGER2 4383/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.