SCHEMBL439648

SCHEMBL439648

Cn1nc(C(F)F)c(C(=O)Cl)c1F

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PTGER4 P35408 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL406709 0.86 MIF (0.33)
SCHEMBL434677 0.84 PTGER4 (0.33) PTGER4
SCHEMBL15237109 0.84 PTGER4 (0.33) PTGER4
SCHEMBL437422 0.84 PTGER4 (0.37) PTGER4
SCHEMBL440487 0.82 L3MBTL1 (0.36) PTGER4
SCHEMBL13723232 0.82 PTGER4 (0.34) PTGER4
SCHEMBL31539136 0.81 PTGER4 (0.30) PTGER4
SCHEMBL221831 0.76 KDM4E (0.42)
SCHEMBL1769176 0.75 PTGER4 (0.31) PTGER4
SCHEMBL6128191 0.73 CA1 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 233 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119954721-A Pyrazole amide derivative, preparation method and application thereof 山东省联合农药工业有限公司 2025-05-09 CN disclosed
CN-110804019-B Amide compound and preparation method and application thereof 上海晓明检测技术服务有限公司 2023-09-12 CN disclosed
EP-4223745-A1 DENDRENE AMIDE COMPOUND, BACTERICIDE AND USE THEREOF Jiangsu Flag Chemical Industry Co., Ltd. (CN) 2023-08-09 EP disclosed
CN-114450269-A Novel method for synthesizing 5-fluoro-3- (difluoromethyl) -5-fluoro-1-methyl-1H-pyrazole-4-carboxylic acid derivative and free acid thereof 福建永晶科技股份有限公司 2022-05-06 CN disclosed
EP-2908642-B1 METHOD FOR ENHANCING TOLERANCE TO ABIOTIC STRESS IN PLANTS BY USING CARBOXAMIDE OR THIOCARBOXAMIDE DERIVATIVES BAYER CROPSCIENCE AG (DE) 2022-02-23 EP disclosed
CN-108347948-B Active compound combinations comprising (thio) carboxamide derivatives and fungicidal compounds 拜耳作物科学股份公司 2021-11-05 CN disclosed
US-10945432-B2 Active compound combinations comprising a (thio)carboxamide derivative and a fungicidal compound BAYER CROPSCIENCE AKTIENGESELLSCHAFT 2021-03-16 US disclosed
US-10945433-B2 Method for treating coffee rust, citrus black spot, citrus scab and banana black sigatoka diseases BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2021-03-16 US disclosed
EP-3367800-B1 ACTIVE COMPOUND COMBINATIONS COMPRISING A (THIO)CARBOXAMIDE DERIVATIVE AND A FUNGICIDAL COMPOUND BAYER CROPSCIENCE AG (DE) 2021-03-10 EP disclosed
CN-107635403-B Methods for treating coffee rust, citrus black spot, citrus scab, and banana black sigatoka disease 拜耳作物科学股份公司 2020-12-04 CN disclosed
US-20110288305-A1 Process for the preparation of 5-Fluoro-1-alkyl-3-fluoroalkyl-1H-pyrazole-4-carbonyl Chlorides and Fluorides BAYER CROPSCIENCE AG (DE) 2011-11-24 US disclosed
US-20110288305-A1 Process for the preparation of 5-Fluoro-1-alkyl-3-fluoroalkyl-1H-pyrazole-4-carbonyl Chlorides and Fluorides BAYER CROPSCIENCE AG (DE) 2011-11-24 US disclosed
WO-2011131615-A1 PROCESS FOR PREPARING 5-FLUORO-1-ALKYL-3-FLUOROALKYL-1H-PYRAZOLE-4-CARBONYL CHLORIDES AND FLUORIDES BAYER CROPSCIENCE AG (DE) 2011-10-27 WO disclosed
US-20110207940-A1 Preparing 5-fluoro-1-alkyl-3-fluoroalkyl-1H-pyrazole-4-carbonyl chlorides BAYER CROPSCIENCE AG (DE) 2011-08-25 US disclosed
US-20110207940-A1 Preparing 5-fluoro-1-alkyl-3-fluoroalkyl-1H-pyrazole-4-carbonyl chlorides BAYER CROPSCIENCE AG (DE) 2011-08-25 US disclosed
US-20110207940-A1 Preparing 5-fluoro-1-alkyl-3-fluoroalkyl-1H-pyrazole-4-carbonyl chlorides BAYER CROPSCIENCE AG (DE) 2011-08-25 US disclosed
WO-2011061205-A1 METHOD FOR PRODUCING 5-FLUORINE-1-ALKYL-3-FLUORALKYL-1H-PYRAZOL-4 CARBOLIC ACID CHLORIDES BAYER CROPSCIENCE AG (DE) 2011-05-26 WO disclosed
EP-2325173-A1 Method for producing 5-fluor-1-alkyl-3-fluoralkyl-1H-pyrazol-4-carboxylic acid chlorides Bayer CropScience AG (DE) 2011-05-25 EP disclosed
WO-2010130767-A2 FUNGICIDE PYRAZOLE CARBOXAMIDES DERIVATIVES BAYER CROPSCIENCE AG (DE) 2010-11-18 WO disclosed
EP-2251331-A1 Fungicide pyrazole carboxamides derivatives Bayer CropScience AG (DE) 2010-11-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110288305-A1 Process for the preparation of 5-Fluoro-1-alkyl-3-fluoroalkyl-1H-pyrazole-4-carbonyl Chlorides and Fluorides AFF4, AFF1, FLI1 PTGER4 4114/4885
US-10945433-B2 Method for treating coffee rust, citrus black spot, citrus scab and banana black sigatoka diseases AMY1A, MANBA, CHIA PTGER4 4628/4885
US-20110207940-A1 Preparing 5-fluoro-1-alkyl-3-fluoroalkyl-1H-pyrazole-4-carbonyl chlorides CBR3, CYP4B1, CYP4F3 PTGER4 4711/4885
US-10945432-B2 Active compound combinations comprising a (thio)carboxamide derivative and a fungicidal compound AADAC, TPMT, PFAS PTGER4 2933/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.