Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | USP7 | Q93009 | 2/20 | 0.32 |
| ▸ | DHFR | P00374 | 1/20 | 0.31 |
| ▸ | HEXA | P06865 | 1/20 | 0.31 |
| ▸ | HEXB | P07686 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2777619 | 0.79 | SMN1; SMN2 (0.40) | NPC1ALDH1A1RAB9AKDM4EHPGD | |
| SCHEMBL14264690 | 0.79 | SMN1; SMN2 (0.40) | NPC1ALDH1A1RAB9AKDM4EHPGD | |
| SCHEMBL5487167 | 0.79 | ALDH1A1 (0.35) | NPC1ALDH1A1RAB9AKDM4EHPGD | |
| SCHEMBL27923911 | 0.77 | MAPT (0.39) | NPC1ALDH1A1RAB9AKDM4EHPGD | |
| SCHEMBL4354037 | 0.76 | SMN1; SMN2 (0.36) | NPC1ALDH1A1RAB9AKDM4EHPGD | |
| SCHEMBL27444686 | 0.75 | NPC1 (0.38) | NPC1ALDH1A1RAB9AKDM4EHPGD | |
| SCHEMBL1639899 | 0.74 | SOAT1 (0.33) | NPC1ALDH1A1RAB9AKDM4EHPGD | |
| Biphenyl SCHEMBL28100853 | 0.74 | ALDH1A1 (0.39) | NPC1ALDH1A1RAB9AKDM4EHPGD | |
| SCHEMBL13978508 | 0.73 | NPC1 (0.31) | NPC1ALDH1A1RAB9AKDM4EHPGD | |
| SCHEMBL4279699 | 0.73 | ADRB2 (0.37) | NPC1ALDH1A1RAB9AKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090054649-A1 | Bridged Organosilane and Production Method Thereof | KABUSHIKI KAISHA TOYOTA CHUO KENKYUSHO (JP) | 2009-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090054649-A1 | Bridged Organosilane and Production Method Thereof | C5, CCNE1, QSOX1 | NPC1 1178/4885ALDH1A1 866/4885RAB9A 1423/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.