Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28359247 | 0.81 | PDE4B (0.42) | KDM4EMAPTMAPK1PDE4BMEN1 | |
| SCHEMBL4346884 | 0.79 | NPC1 (0.32) | ALDH1A1NPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL4279699 | 0.78 | ADRB2 (0.37) | ALDH1A1NPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL27923911 | 0.75 | MAPT (0.39) | ALDH1A1NPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL29002751 | 0.75 | PDE4B (0.41) | ALDH1A1NPC1RAB9AHPGDKDM4E | |
| SCHEMBL5488456 | 0.75 | ALDH1A1 (0.33) | ALDH1A1NPC1RAB9AHPGDSMN1; SMN2 | |
| Benzene SCHEMBL28867986 | 0.72 | LTA4H (0.37) | ALDH1A1NPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL545764 | 0.72 | CD274 (0.35) | ALDH1A1NPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL1639899 | 0.72 | SOAT1 (0.33) | ALDH1A1NPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL12815342 | 0.72 | METAP2 (0.41) | ALDH1A1RAB9AHPGDSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291747-B2 | Silicon compounds and process for preparation thereof | CHISSO CORPORATION (JP) | 2007-11-06 | — | — | US | disclosed |
| US-20040143081-A1 | Novel silicon compounds and process for preparation thereof | JNC CORPORATION (JP) | 2004-07-22 | — | — | US | disclosed |