Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 12/20 | 0.48 |
| ▸ | MMP3 | P08254 | 7/20 | 0.48 |
| ▸ | RORC | P51449 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4031469 | 0.86 | MMP8 (0.50) | MMP8MMP3RORCATMPOLB | |
| SCHEMBL4036169 | 0.85 | MMP8 (0.48) | MMP8MMP3RORCMCL1PTGER3 | |
| SCHEMBL929394 | 0.85 | RORC (0.43) | MMP8MMP3RORCPTGER3 | |
| SCHEMBL4845158 | 0.82 | MMP8 (0.58) | MMP8MMP3MCL1POLB | |
| SCHEMBL1043997 | 0.81 | MMP8 (0.45) | MMP8MMP3RORCMCL1PTGER3 | |
| SCHEMBL4840536 | 0.81 | MMP8 (0.45) | MMP8MMP3RORCMCL1PTGER3 | |
| SCHEMBL4843338 | 0.80 | LMNA (0.46) | MMP8MMP3RORCATMPOLB | |
| SCHEMBL4840519 | 0.80 | MMP8 (0.44) | MMP8MMP3RORCMCL1PTGER3 | |
| SCHEMBL4035728 | 0.80 | PSEN1 (0.51) | MMP8MMP3POLB | |
| SCHEMBL4843221 | 0.79 | MMP8 (0.52) | MMP8MMP3MCL1POLBMMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1885695-B1 | INDOLINE COMPOUNDS | FOURNIER LAB SA (FR) | 2009-02-25 | — | — | EP | disclosed |