Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 4/20 | 0.50 |
| ▸ | MMP3 | P08254 | 3/20 | 0.50 |
| ▸ | RORC | P51449 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4843338 | 0.89 | LMNA (0.46) | MMP8MMP3RORCALDH1A1PKM | |
| SCHEMBL5250841 | 0.87 | ALDH1A1 (0.53) | MMP8MMP3ALDH1A1PKMFKBP1A | |
| SCHEMBL4347387 | 0.86 | MMP8 (0.48) | MMP8MMP3RORCATMTRPA1 | |
| SCHEMBL4036169 | 0.86 | MMP8 (0.48) | MMP8MMP3RORCATM | |
| SCHEMBL3827372 | 0.85 | RORC (0.46) | MMP8MMP3RORCTRPA1 | |
| SCHEMBL4844332 | 0.84 | MEN1 (0.40) | MMP8MMP3RORCFKBP1AATM | |
| SCHEMBL1043993 | 0.84 | TRPA1 (0.40) | MMP8MMP3RORCFKBP1AATM | |
| SCHEMBL926836 | 0.84 | FKBP1A (0.48) | RORCALDH1A1PKMFKBP1ALMNA | |
| SCHEMBL4845158 | 0.84 | MMP8 (0.58) | MMP8MMP3LMNAPOLB | |
| SCHEMBL926215 | 0.84 | PSEN1 (0.51) | MMP8MMP3ALDH1A1FKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1885695-B1 | INDOLINE COMPOUNDS | FOURNIER LAB SA (FR) | 2009-02-25 | — | — | EP | disclosed |
| US-7465811-B2 | Indoline compounds | LABORATOIRES FOURNIER S.A. (FR) | 2008-12-16 | — | — | US | disclosed |
| US-20080119465-A1 | Novel Indoline Compounds | LABORATORIES FOURNIER S.A. (FR) | 2008-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080119465-A1 | Novel Indoline Compounds | GPR119, INSR, IRS1 | MMP8 3968/4885MMP3 3739/4885RORC 1777/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.