Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1G | O43497 | 1/20 | 0.37 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 15/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 15/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4348259 | 0.82 | CACNA1G (0.37) | CACNA1GCACNA1HHCRTR1HCRTR2KCNH2 | |
| SCHEMBL4103942 | 0.78 | KCNH2 (0.40) | HCRTR1HCRTR2KCNH2 | |
| SCHEMBL14447537 | 0.76 | KCNH2 (0.48) | HCRTR1HCRTR2KCNH2 | |
| SCHEMBL1440519 | 0.70 | GRIN2D (0.47) | — | |
| SCHEMBL14838875 | 0.70 | SCN10A (0.52) | HCRTR1HCRTR2 | |
| Hydrochloric Acid SCHEMBL1440681 | 0.69 | GRIN2D (0.46) | — | |
| SCHEMBL19197040 | 0.68 | KCNH2 (0.47) | HCRTR1HCRTR2KCNH2 | |
| SCHEMBL4356646 | 0.68 | HRH4 (0.45) | CACNA1GCACNA1HHCRTR1HCRTR2 | |
| SCHEMBL8264566 | 0.67 | ALDH1A1 (0.56) | — | |
| SCHEMBL1515586 | 0.67 | TAAR1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7504426-B2 | Heterocyclic compounds | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-03-17 | — | — | US | disclosed |