SCHEMBL434854

SCHEMBL434854

O=C(O)c1cc(C(=O)O)c(C(=O)O)c(C(F)(F)F)c1C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.41
HPGD P15428 3/20 0.41
KDM4E B2RXH2 2/20 0.41
HSD17B10 Q99714 2/20 0.41
NOTUM Q6P988 2/20 0.41
ASPH Q12797 1/20 0.40
RXRA P19793 2/20 0.40
RXRB P28702 2/20 0.40
RXRG P48443 1/20 0.37
USP2 O75604 1/20 0.36
CYP2C19 P33261 1/20 0.36
CYP1A2 P05177 2/20 0.33
ALOX15 P16050 1/20 0.33
MEN1 O00255 1/20 0.33
ALOX12 P18054 1/20 0.33
KMT2A Q03164 1/20 0.33
GLRA3 O75311 1/20 0.33
GLRB P48167 1/20 0.33
MAPT P10636 2/20 0.33
POLB P06746 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1099692 0.85 ALDH1A1 (0.38) ALDH1A1HPGDKDM4EHSD17B10NOTUM
SCHEMBL3185981 0.83 ALDH1A1 (0.35) ALDH1A1HPGDKDM4EHSD17B10NOTUM
SCHEMBL1100670 0.82 ASPH (0.42) ALDH1A1HPGDKDM4EHSD17B10NOTUM
SCHEMBL11745002 0.81 ALDH1A1 (0.34) ALDH1A1HPGDKDM4EHSD17B10NOTUM
SCHEMBL436571 0.80 GPR35 (0.38) ALDH1A1HPGDKDM4EHSD17B10NOTUM
SCHEMBL28187804 0.79 NOTUM (0.33) ALDH1A1HPGDKDM4EHSD17B10NOTUM
SCHEMBL1098875 0.77 ASPH (0.44) ALDH1A1HPGDKDM4EHSD17B10NOTUM
SCHEMBL1099462 0.77 ALDH1A1 (0.42) ALDH1A1HPGDKDM4EHSD17B10NOTUM
SCHEMBL29404413 0.77 ASPH (0.44) ALDH1A1HPGDKDM4EHSD17B10NOTUM
SCHEMBL7090621 0.77 MEN1 (0.53) ALDH1A1HPGDKDM4EHSD17B10CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 281 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115895255-B Preparation method of carbon nanotube modified silicon oxide composite material, product and application thereof 浙江锂宸新材料科技有限公司 2024-05-17 CN claimed
CN-118005921-A High-transparency polyimide film material for flexible display and preparation method thereof 大连理工大学盘锦产业技术研究院 2024-05-10 CN claimed
CN-117736472-A Preparation method of color-adjustable fluorine polyimide film 厦门大学 2024-03-22 CN claimed
CN-117402172-A Synthesis method of 3, 6-bis (trifluoromethyl) -pyromellitic dianhydride 中国科学院上海有机化学研究所 2024-01-16 CN claimed
CN-114908438-B Polyimide aerogel fiber based on coaxial spinning and preparation method thereof 东华大学 2023-09-08 CN claimed
CN-114790289-B Preparation method of high-temperature-resistant polyimide resin 中国船舶重工集团公司第七一八研究所 2023-08-11 CN claimed
CN-114621436-B High heat-resistant transparent polyimide film, preparation method and application 深圳瑞华泰薄膜科技股份有限公司 2023-04-07 CN claimed
CN-115895255-A Preparation method of carbon nanotube modified silica composite material, product and application thereof 浙江锂宸新材料科技有限公司 2023-04-04 CN claimed
CN-115850596-A Transparent photosensitive polyimide resin and preparation method and application thereof 中国科学院化学研究所 2023-03-28 CN claimed
CN-111876085-B Composite bonding sheet, flexible metal laminated board and preparation method thereof 东莞东阳光科研发有限公司 2022-09-27 CN claimed
CN-106750443-B Thermoplastic polyimide prepreg and preparation method of composite material thereof 自贡中天胜新材料科技有限公司 2020-03-20 CN claimed
CN-110669336-A Modified fluorine-containing polyimide resin composition and preparation method thereof 中山市鸿盛新材料有限公司 2020-01-10 CN claimed
US-20070009751-A1 Polyamic acid resin composition modified with laminate nanometer silica sheet and polyimide prepared therefrom CHANG CHUN PLASTICS CO., LTD. (TW) 2007-01-11 US claimed
CN-1282713-C Photosensitive polyimide resin precursor composition, optical polyimide, light wave guide tube and process for producing the same light wave guide tube NITTO DENKO CORP (JP) 2006-11-01 CN claimed
US-7005163-B2 Organic-inorganic hybrid film material and its fabrication CHANG CHUN PLASTICS CO., LTD. (TW) 2006-02-28 US claimed
US-20040110014-A1 Organic-inorganic hybrid film material and its fabrication CHANG CHUN PLASTICS CO., LTD. (TW) 2004-06-10 US claimed
CN-1468907-A Photosensitive polyimide resin precursor composition, optical polyimide, light wave guide tube and process for producing the same light wave guide tube �ն��繤��ʽ���� 2004-01-21 CN claimed
EP-0400635-B1 Liquid crystal device CANON KK (JP) 1995-09-27 EP claimed
US-5192596-A Polyimide CANON KABUSHIKI KAISHA (JP) 1993-03-09 US claimed
EP-0400635-A2 Liquid crystal device CANON KABUSHIKI KAISHA (JP) 1990-12-05 EP claimed