SCHEMBL4348669

SCHEMBL4348669

CC(c1cccs1)S(=O)(=O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.46
CES2 O00748 1/20 0.42
CES1 P23141 1/20 0.42
KEAP1 Q14145 1/20 0.42
GAA P10253 2/20 0.40
RAB9A P51151 2/20 0.39
MAPT P10636 2/20 0.38
ALDH1A1 P00352 3/20 0.38
HPGD P15428 2/20 0.38
F2 P00734 1/20 0.38
PRSS1 P07477 1/20 0.38
PRSS2 P07478 1/20 0.38
PRSS3 P35030 1/20 0.38
NPC1 O15118 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.36
LMNA P02545 3/20 0.36
TSHR P16473 2/20 0.36
GFER P55789 1/20 0.36
KMT2A Q03164 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10745318 0.83 GAA (0.45) ALOX5CES2CES1KEAP1GAA
SCHEMBL1417567 0.83 ALOX5 (0.44) ALOX5CES2CES1KEAP1GAA
SCHEMBL29003427 0.76 ALOX5 (0.42) ALOX5CES2CES1KEAP1GAA
SCHEMBL10741651 0.76 RAB9A (0.46) ALOX5RAB9AMAPTALDH1A1LMNA
SCHEMBL5348205 0.75 ALOX5 (0.43) ALOX5CES2CES1KEAP1GAA
SCHEMBL11212893 0.73 CES2 (0.43) ALOX5CES2CES1KEAP1RAB9A
SCHEMBL9782245 0.73 CES2 (0.40) ALOX5CES2CES1KEAP1GAA
SCHEMBL5298683 0.72 ALOX5 (0.42) ALOX5CES2CES1KEAP1GAA
SCHEMBL11212896 0.72 ALOX5 (0.46) ALOX5CES2CES1KEAP1RAB9A
SCHEMBL332333 0.72 LMNA (0.43) ALOX5CES2CES1KEAP1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120136918-A Method for preparing 4- (2, 2-diaryl vinyl) thiophosphorus/phosphonate 岳阳凯茂化工材料有限公司 2025-06-13 CN claimed
EP-1141335-B1 CHEMICALLY MODIFIED ENZYMES WITH MULTIPLE CHARGED VARIANTS GENENCOR INT (US) 2009-08-05 EP claimed
US-7371553-B2 Chemically modified enzymes with multiple charged variants GENENCOR INTERNATIONAL, INC. (US) 2008-05-13 US claimed
US-20020127695-A1 Chemically modified enzymes with multiple charged variants GENENCOR INTERNATIONAL, INC. 2002-09-12 US claimed
US-6379942-B1 SUBTILISIN ENZYME, WITH CYSTEINE RESIDUES AT GIVE AMINO ACID SEQUENCE POSITIONS, WHERE THE THIOL HYDROGEN IN THE CYSTEINE RESIDUE IS REPLACED, PROVIDING A SIDE CHAIN IWTH A MULTIPLY CHARGED MOIETY; DETERGENTS GENENCOR INTERNATIONAL, INC. 2002-04-30 US claimed
EP-1141335-A2 CHEMICALLY MODIFIED ENZYMES WITH MULTIPLE CHARGED VARIANTS GENENCOR INTERNATIONAL, INC. (US) 2001-10-10 EP claimed
WO-2000037658-A2 CHEMICALLY MODIFIED ENZYMES WITH MULTIPLE CHARGED VARIANTS GENENCOR INTERNATIONAL, INC. (US) 2000-06-29 WO claimed
EP-1141335-B1 CHEMICALLY MODIFIED ENZYMES WITH MULTIPLE CHARGED VARIANTS GENENCOR INT (US) 2009-08-05 EP disclosed
US-7371553-B2 Chemically modified enzymes with multiple charged variants GENENCOR INTERNATIONAL, INC. (US) 2008-05-13 US disclosed
US-20050089966-A1 Chemically modified enzymes with multiple charged variants DAVID BENJAMIN G (GB) 2005-04-28 US disclosed
US-20020127695-A1 Chemically modified enzymes with multiple charged variants GENENCOR INTERNATIONAL, INC. 2002-09-12 US disclosed
US-6379942-B1 SUBTILISIN ENZYME, WITH CYSTEINE RESIDUES AT GIVE AMINO ACID SEQUENCE POSITIONS, WHERE THE THIOL HYDROGEN IN THE CYSTEINE RESIDUE IS REPLACED, PROVIDING A SIDE CHAIN IWTH A MULTIPLY CHARGED MOIETY; DETERGENTS GENENCOR INTERNATIONAL, INC. 2002-04-30 US disclosed
EP-1141335-A2 CHEMICALLY MODIFIED ENZYMES WITH MULTIPLE CHARGED VARIANTS GENENCOR INTERNATIONAL, INC. (US) 2001-10-10 EP disclosed
WO-2000037658-A2 CHEMICALLY MODIFIED ENZYMES WITH MULTIPLE CHARGED VARIANTS GENENCOR INTERNATIONAL, INC. (US) 2000-06-29 WO disclosed