Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.55 |
| ▸ | CES1 | P23141 | 1/20 | 0.55 |
| ▸ | PARP1 | P09874 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3165423 | 0.83 | CES2 (0.52) | CES2CES1PARP1LMNAKDM4E | |
| SCHEMBL6099390 | 0.82 | ERCC5 (0.50) | LMNAKDM4EKMT2AHPGDHTT | |
| SCHEMBL2056918 | 0.81 | MEN1 (0.56) | CES2CES1PARP1LMNAKDM4E | |
| SCHEMBL7649275 | 0.80 | CES2 (0.49) | CES2CES1PARP1LMNAKDM4E | |
| SCHEMBL7647919 | 0.80 | CES2 (0.49) | CES2CES1PARP1LMNAKDM4E | |
| SCHEMBL1210113 | 0.80 | CTNNB1 (0.58) | PARP1LMNAKDM4ENPC1KMT2A | |
| SCHEMBL7285469 | 0.80 | ESR1 (0.53) | PARP1KDM4ENPC1MAPTRAB9A | |
| SCHEMBL11267206 | 0.80 | KMT2A (0.47) | KMT2AHPGDRAB9ASMN1; SMN2HSD17B10 | |
| SCHEMBL31309786 | 0.80 | CTNNB1 (0.58) | PARP1LMNAKDM4ENPC1KMT2A | |
| SCHEMBL16994152 | 0.80 | MEN1 (0.46) | LMNAKDM4ENPC1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260028600-A1 | TRANSAMINASE POLYPEPTIDES | CODEXIS INC (US) | 2026-01-29 | — | — | US | disclosed |
| US-12448611-B2 | Transaminase polypeptides | CODEXIS, INC. (US) | 2025-10-21 | — | — | US | disclosed |
| EP-4608802-A1 | USE OF STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI CONTAINING AN AMINO ACID SUBSTITUTION F129L IN THE MITOCHONDRIAL CYTOCHROME B PROTEIN CONFERRING RESISTANCE TO QO INHIBITORS XV | BASF SE (DE) | 2025-09-03 | — | — | EP | disclosed |
| US-12378537-B2 | Biocatalysts and methods for synthesizing derivatives of tryptamine and tryptamine analogs | CODEXIS, INC. (US) | 2025-08-05 | — | — | US | disclosed |
| CN-120091993-A | Use of strobilurin type compounds for combating phytopathogenic fungi comprising the amino acid substitution F129L in the mitochondrial cytochrome b protein conferring resistance to Qo inhibitor XV | 巴斯夫欧洲公司 | 2025-06-03 | — | — | CN | disclosed |
| US-12305201-B2 | Engineered biocatalysts and methods for synthesizing chiral amines | CODEXIS, INC. (US) | 2025-05-20 | — | — | US | disclosed |
| US-20250101389-A1 | BIOCATALYSTS AND METHODS FOR THE SYNTHESIS OF SUBSTITUTED LACTAMS | CODEXIS INC (US) | 2025-03-27 | — | — | US | disclosed |
| CN-119698468-A | Biocatalysts and methods thereof | 特沙诺有限公司 | 2025-03-25 | — | — | CN | disclosed |
| US-12163162-B2 | Biocatalysts and methods for the synthesis of substituted lactams | CODEXIS, INC. (US) | 2024-12-10 | — | — | US | disclosed |
| US-20240150732-A1 | TRANSAMINASE POLYPEPTIDES | INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT | 2024-05-09 | — | — | US | disclosed |
| EP-1075534-B8 | IMPROVEMENTS IN THE ENZYMATIC SYNTHESIS OF CHIRAL AMINES | CELGRO (US) | 2005-07-06 | — | — | EP | disclosed |
| EP-1075534-B1 | IMPROVEMENTS IN THE ENZYMATIC SYNTHESIS OF CHIRAL AMINES | CELGRO (US) | 2005-05-11 | — | — | EP | disclosed |
| EP-1075534-A4 | IMPROVEMENTS IN THE ENZYMATIC SYNTHESIS OF CHIRAL AMINES | CELGRO (US) | 2003-07-09 | — | — | EP | disclosed |
| EP-1075534-A1 | IMPROVEMENTS IN THE ENZYMATIC SYNTHESIS OF CHIRAL AMINES | Celgro (US) | 2001-02-14 | — | — | EP | disclosed |
| US-6133018-A | Enzymatic synthesis of chiral amines using -2-amino propane as amine donor | CELGRO (US) | 2000-10-17 | — | — | US | disclosed |
| WO-1999046398-A1 | IMPROVEMENTS IN THE ENZYMATIC SYNTHESIS OF CHIRAL AMINES | CELGRO (US) | 1999-09-16 | — | — | WO | disclosed |
| EP-0203791-B1 | SPIRO-IMIDAZOLIDINES AS ALDOSE REDUCTASE INHIBITORS | PFIZER INC. (US) | 1989-09-13 | — | — | EP | disclosed |
| EP-0203791-A1 | Spiro-imidazolidines as aldose reductase inhibitors | PFIZER INC. (US) | 1986-12-03 | — | — | EP | disclosed |
| US-4575507-A | COMPLICATIONS OF DIABETES | PFIZER INC. (US) | 1986-03-11 | — | — | US | disclosed |
| US-4251546-A | Process for killing internal helminths using certain 1,1-bis-(2-substituted-3-nitrophenyl)alkane or alkylene derivatives | ICI AUSTRALIA LIMITED (AU) | 1981-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250101389-A1 | BIOCATALYSTS AND METHODS FOR THE SYNTHESIS OF SUBSTITUTED LACTAMS | BCAT1, GOT1, OAT | CES2 176/4885CES1 192/4885PARP1 1304/4885 |
| US-20260028600-A1 | TRANSAMINASE POLYPEPTIDES | GOT1, OAT, PEPD | CES2 419/4885CES1 100/4885PARP1 1345/4885 |
| US-12163162-B2 | Biocatalysts and methods for the synthesis of substituted lactams | BCAT1, GOT1, OAT | CES2 176/4885CES1 192/4885PARP1 1304/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.