Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BBOX1 | O75936 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 5/20 | 0.37 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL692963 | 0.94 | BBOX1 (0.37) | BBOX1KDM4EMAPTALOX15SMN1; SMN2 | |
| SCHEMBL29276294 | 0.94 | CYP2C19 (0.41) | BBOX1KDM4EMAPTALOX15SMN1; SMN2 | |
| SCHEMBL30831235 | 0.94 | BBOX1 (0.37) | BBOX1KDM4EMAPTALOX15SMN1; SMN2 | |
| SCHEMBL150760 | 0.94 | KDM4E (0.42) | BBOX1KDM4EMAPTALOX15SMN1; SMN2 | |
| Potassium Ion SCHEMBL4411096 | 0.86 | — | — | |
| SCHEMBL31636033 | 0.84 | KDM4E (0.37) | BBOX1KDM4EMAPTALOX15SMN1; SMN2 | |
| SCHEMBL28432505 | 0.82 | KDM4E (0.35) | KDM4EMAPTALOX15SMN1; SMN2CA4 | |
| Potassium Ion SCHEMBL27236426 | 0.82 | MAPT (0.50) | BBOX1KDM4EMAPTALOX15SMN1; SMN2 | |
| Potassium Ion SCHEMBL156772 | 0.81 | — | — | |
| Potassium Ion SCHEMBL4790824 | 0.77 | S1PR2 (0.44) | CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0858001-B1 | Photographic bleaching solution containing organic phosphorus acid anti-rust agent and method of use | EASTMAN KODAK CO (US) | 2004-12-08 | — | — | EP | disclosed |
| US-6197483-B1 | BLEACHING IMAGEWISE EXPOSED AND COLOR DEVELOPED PHOTOGRAPHIC SILVER HALIDE ELEMENT; FIXING WITH FIXING AGENT AND CITRIC ACID AND ETHYLENEDIAMINEDISUCCINIC ACID OR MIXTURES | EASTMAN KODAK COMPANY | 2001-03-06 | — | — | US | disclosed |
| EP-0858001-A1 | Photographic bleaching solution containing organic phosphorus acid anti-rust agent and method of use | EASTMAN KODAK COMPANY (US) | 1998-08-12 | — | — | EP | disclosed |