Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7073284 | 0.76 | THRB (0.51) | THRBTHRA | |
| SCHEMBL1581472 | 0.76 | THRA (0.58) | THRBTHRA | |
| SCHEMBL3221725 | 0.75 | THRB (0.51) | THRBTHRA | |
| SCHEMBL8636369 | 0.75 | THRA (0.55) | THRBTHRA | |
| SCHEMBL7073643 | 0.74 | THRA (0.49) | THRBTHRA | |
| SCHEMBL7073286 | 0.73 | THRA (0.48) | THRBTHRA | |
| SCHEMBL27666404 | 0.72 | THRA (0.59) | THRBTHRA | |
| SCHEMBL8635703 | 0.72 | LTA4H (0.58) | THRBTHRA | |
| SCHEMBL4561125 | 0.71 | THRA (0.74) | THRBTHRA | |
| SCHEMBL8636953 | 0.70 | THRA (0.50) | THRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009080835-A1 | THYROMIMETRIC COMPOUNDS IN TREATMENT OF DISEASE RELATED TO SONIC HEDGEHOG SIGNALLING | KARO BIO AB (SE) | 2009-07-02 | — | — | WO | disclosed |