Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2965044 | 0.79 | ADORA3 (0.38) | ADORA3CSNK2A1 | |
| SCHEMBL11007131 | 0.76 | — | — | |
| SCHEMBL12592352 | 0.72 | ADORA3 (0.35) | ADORA3PARP1CSNK2A1ALDH1A1L3MBTL1 | |
| SCHEMBL2953678 | 0.71 | ADORA3 (0.38) | ADORA3PARP1CSNK2A1ALDH1A1L3MBTL1 | |
| SCHEMBL20564 | 0.71 | ADORA3 (0.38) | ADORA3PARP1CSNK2A1ALDH1A1L3MBTL1 | |
| SCHEMBL2346673 | 0.71 | — | — | |
| SCHEMBL953009 | 0.69 | NUDT1 (0.41) | ADORA3PARP1 | |
| SCHEMBL19633362 | 0.68 | CDK1 (0.37) | ADORA3PARP1CSNK2A1ALDH1A1L3MBTL1 | |
| SCHEMBL6153814 | 0.63 | — | — | |
| SCHEMBL4298076 | 0.62 | MEN1 (0.39) | ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024135721-A1 | METHOD FOR PRODUCING PRODUCTION INTERMEDIATE, PRODUCTION INTERMEDIATE THEREOF, AND METHOD FOR PRODUCING CROSSLINKED ARTIFICIAL NUCLEIC ACID INTERMEDIATE BY USING SAME | 田辺三菱製薬株式会社 | 2024-06-27 | — | — | WO | disclosed |
| US-7612197-B2 | Reacting a nucleophil with OH group with an electrophil to form an adduct, reacting adduct with a reagent selected from oxidizing, sulfurizing or selenizing agents to produce hydroxy protected oligonucleotide, heating to deprotect hydroxy protecting group such as 2-(2-pyridyl)aminoethoxycarbonyl | The United States of America as repesented by the Secretary of the Department of Health and Human Services (US) | 2009-11-03 | — | — | US | disclosed |
| US-7355037-B2 | Thermolabile hydroxyl protecting groups and methods of use | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2008-04-08 | — | — | US | disclosed |
| US-20060281911-A1 | Thermolabile hydroxyl protecting groups and methods of use | GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH (US) | 2006-12-14 | — | — | US | disclosed |
| US-20050020827-A1 | Thermolabile hydroxyl protecting groups and methods of use | GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES | 2005-01-27 | — | — | US | disclosed |
| WO-2004101582-A2 | THERMOLABILE HYDROXYL PROTECTING GROUPS AND METHODS OF USE | GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2004-11-25 | — | — | WO | disclosed |
| WO-2003048179-A2 | THERMOLABILE HYDROXYL PROTECTING GROUPS AND METHODS OF USE | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2003-06-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050020827-A1 | Thermolabile hydroxyl protecting groups and methods of use | ADH1A, NR2C2, NR1H2 | ADORA3 419/4885PARP1 3007/4885CSNK2A1 185/4885 |
| US-20060281911-A1 | Thermolabile hydroxyl protecting groups and methods of use | ADH1A, CYP2E1, ADH1C | ADORA3 292/4885PARP1 642/4885CSNK2A1 1840/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.