SCHEMBL435200

SCHEMBL435200

CCCCn1c2ccc(Br)cc2c2cc(Br)ccc21

nearest known ligand 0.56

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 1/20 0.56
MAPT P10636 3/20 0.49
SMN1; SMN2 Q16637 2/20 0.48
ALDH1A1 P00352 1/20 0.48
RORA P35398 6/20 0.48
RORC P51449 6/20 0.48
RORB Q92753 6/20 0.48
PGR P06401 5/20 0.48
DNM1 Q05193 3/20 0.46
TSPO P30536 1/20 0.44
PSEN1 P49768 1/20 0.44
PSEN2 P49810 1/20 0.44
APH1B Q8WW43 1/20 0.44
NCSTN Q92542 1/20 0.44
APH1A Q96BI3 1/20 0.44
PSENEN Q9NZ42 1/20 0.44
CNR2 P34972 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11909992 0.95 SIGMAR1 (0.55) SIGMAR1MAPTSMN1; SMN2ALDH1A1DNM1
SCHEMBL3823482 0.93 SIGMAR1 (0.54) SIGMAR1MAPTSMN1; SMN2RORARORC
SCHEMBL3339737 0.93 SIGMAR1 (0.54) SIGMAR1MAPTSMN1; SMN2RORARORC
SCHEMBL28299672 0.93 SIGMAR1 (0.54) SIGMAR1MAPTSMN1; SMN2RORARORC
SCHEMBL751367 0.93 SIGMAR1 (0.54) SIGMAR1MAPTSMN1; SMN2RORARORC
SCHEMBL11127173 0.93 SIGMAR1 (0.54) SIGMAR1MAPTSMN1; SMN2RORARORC
SCHEMBL17704933 0.92 RORA (0.59) SIGMAR1MAPTSMN1; SMN2ALDH1A1RORA
SCHEMBL1921471 0.92 PGR (0.56) SIGMAR1ALDH1A1RORARORCRORB
SCHEMBL10869247 0.91 SIGMAR1 (0.49) SIGMAR1MAPTSMN1; SMN2ALDH1A1RORA
SCHEMBL926107 0.90 PSEN1 (0.53) SIGMAR1MAPTPSEN1PSEN2APH1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117105846-A Diamine monomer, synthesis method thereof and application of diamine monomer in preparation of polyimide 慧迈材料科技(广东)有限公司 2023-11-24 CN claimed
CN-117105846-A Diamine monomer, synthesis method thereof and application of diamine monomer in preparation of polyimide 慧迈材料科技(广东)有限公司 2023-11-24 CN disclosed
US-9447040-B2 Tricyclic compounds, compositions comprising them and uses thereof YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) 2016-09-20 US disclosed
US-9346756-B2 Electro-fluorescent emitter for ultra-violet OLED NATIONAL TSING HUA UNIVERSITY (TW) 2016-05-24 US disclosed
US-9346756-B2 Electro-fluorescent emitter for ultra-violet OLED NATIONAL TSING HUA UNIVERSITY (TW) 2016-05-24 US disclosed
US-9346756-B2 Electro-fluorescent emitter for ultra-violet OLED NATIONAL TSING HUA UNIVERSITY (TW) 2016-05-24 US disclosed
CN-105586029-A Luminescent material of ultraviolet organic light emitting diode ZHOU ZHUOYUN 2016-05-18 CN disclosed
US-20160115127-A1 Electro-fluorescent emitter for ultra-violet OLED NATIONAL TSING HUA UNIVERSITY (TAIWAN) (TW) 2016-04-28 US disclosed
US-20160115127-A1 Electro-fluorescent emitter for ultra-violet OLED NATIONAL TSING HUA UNIVERSITY (TAIWAN) (TW) 2016-04-28 US disclosed
US-20160115127-A1 Electro-fluorescent emitter for ultra-violet OLED NATIONAL TSING HUA UNIVERSITY (TAIWAN) (TW) 2016-04-28 US disclosed
EP-2327739-A1 Novel triarylamine polymer, process for its production and its use TOSOH CORPORATION (JP) 2011-06-01 EP disclosed
US-20100026168-A1 Hole Transport Material NATIONAL TAIWAN UNIVERSITY (TW) 2010-02-04 US disclosed
US-7608680-B2 Triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2009-10-27 US disclosed
US-20080230776-A1 Organic semiconductor material and organic transistor using the same SANYO ELECTRIC CO., LTD. (JP) 2008-09-25 US disclosed
US-20060241278-A1 Novel triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2006-10-26 US disclosed
US-20060017040-A9 Novel triarylamine polymer, process for producing the same, and use thereof SUZUKI TAKAO 2006-01-26 US disclosed
US-20050186106-A1 Organic electroluminescent device and process for preparing the same SANYO ELECTRIC CO., LTD. 2005-08-25 US disclosed
EP-1528074-A1 NOVEL TRIARYLAMINE POLYMER, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF Tosoh Corporation (JP) 2005-05-04 EP disclosed
US-20040262574-A1 Novel triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2004-12-30 US disclosed
US-6034206-A POLYANILINES; HEAT, CHEMICAL AND SOLVENT RESISTANCE TOSOH CORPORATION (JP) 2000-03-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160115127-A1 Electro-fluorescent emitter for ultra-violet OLED CACNA2D2, CACNA2D1, CACNA2D3 SIGMAR1 2663/4885MAPT 1960/4885SMN1; SMN2 4669/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.