Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | PTGFR | P43088 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13064249 | 0.88 | TSHR (0.50) | RAB9ARECQLMEN1KMT2AHTT | |
| SCHEMBL1044642 | 0.87 | MAPT (0.45) | RAB9ARECQLMEN1KMT2AHTT | |
| SCHEMBL1877272 | 0.87 | NTRK1 (0.49) | RAB9ARECQLMEN1KMT2AMAPT | |
| SCHEMBL13210721 | 0.81 | NTRK1 (0.43) | RAB9ARECQLMEN1KMT2AHTT | |
| SCHEMBL343339 | 0.80 | TDP1 (0.47) | RAB9ARECQLMEN1KMT2AHTT | |
| SCHEMBL13210713 | 0.80 | MAPT (0.41) | RAB9ARECQLMEN1KMT2AHTT | |
| SCHEMBL29437136 | 0.80 | MAPT (0.41) | RAB9ARECQLMEN1KMT2AHTT | |
| SCHEMBL167980 | 0.80 | MAPT (0.41) | RAB9ARECQLMEN1KMT2AHTT | |
| SCHEMBL2911307 | 0.79 | RAB9A (0.46) | RAB9ARECQLMEN1KMT2AHTT | |
| SCHEMBL13210784 | 0.79 | KMT2A (0.42) | RAB9AMEN1KMT2AHTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2132989-A2 | Agent combinations | Bayer CropScience AG (DE) | 2009-12-16 | — | — | EP | disclosed |