SCHEMBL435474

SCHEMBL435474

O=C(O)c1cccc(-c2ncccn2)c1O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HNF4A P41235 1/20 0.59
KDM4E B2RXH2 6/20 0.50
TDP1 Q9NUW8 1/20 0.50
ALDH1A1 P00352 6/20 0.49
L3MBTL1 Q9Y468 3/20 0.48
HSD17B10 Q99714 2/20 0.48
ALOX15 P16050 2/20 0.48
HPGD P15428 2/20 0.48
ALB P02768 1/20 0.48
CYP3A4 P08684 1/20 0.48
MAPT P10636 1/20 0.48
TSHR P16473 1/20 0.48
BLM P54132 1/20 0.48
AGER Q15109 1/20 0.48
NPSR1 Q6W5P4 1/20 0.48
MMP2 P08253 1/20 0.48
NAPRT Q6XQN6 3/20 0.47
LMNA P02545 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
ALOX12 P18054 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9592605 0.84 PARP1 (0.50) HNF4AKDM4EALDH1A1L3MBTL1HSD17B10
SCHEMBL465563 0.82 KDM4E (0.55) HNF4AKDM4ETDP1ALDH1A1L3MBTL1
SCHEMBL5678745 0.82 HNF4A (0.76) HNF4AKDM4EALDH1A1L3MBTL1HSD17B10
SCHEMBL8102349 0.81 KDM4E (0.50) HNF4AKDM4ETDP1ALDH1A1L3MBTL1
SCHEMBL28455317 0.81 KDM4E (0.50) HNF4AKDM4ETDP1ALDH1A1L3MBTL1
SCHEMBL9235039 0.81 HNF4A (0.59) HNF4AKDM4ETDP1ALDH1A1L3MBTL1
SCHEMBL126694 0.80 KDM4E (0.48) HNF4AKDM4ETDP1ALDH1A1L3MBTL1
SCHEMBL7751865 0.80 NAPRT (0.55) HNF4AKDM4ETDP1ALDH1A1L3MBTL1
SCHEMBL10948911 0.80 HNF4A (0.73) HNF4AKDM4EALDH1A1L3MBTL1HSD17B10
SCHEMBL17336670 0.79 KDM4E (0.52) KDM4ETDP1ALDH1A1L3MBTL1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 292 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115124477-A Novel pyrimidine salicylic acid phenolic ester, synthetic method thereof and application thereof as herbicide 中国农业大学 2022-09-30 CN claimed
CN-112029742-B ALS mutant protein of plant and application thereof 天津市农业科学院 2022-03-15 CN claimed
CN-112998025-A Weeding composition containing substituted pyrazolyl pyrazole sulfonylurea compound 海利尔药业集团股份有限公司 2021-06-22 CN claimed
CN-112029742-A ALS mutant protein of plant and application thereof 天津市农业科学院 2020-12-04 CN claimed
US-8466088-B2 Herbicidal compositions containing benzoylpyrazole compounds ISHIHARA SANGYO KAISHA, LTD. (JP) 2013-06-18 US claimed
US-20110263427-A1 HERBICIDAL COMPOSITIONS CONTAINING BENZOYLPYRAZOLE COMPOUNDS ISHIHARA SANGYO KAISHA, LTD (JP) 2011-10-27 US claimed
EP-2365754-A1 HERBICIDAL COMPOSITIONS CONTAINING BENZOYLPYRAZOLE COMPOUNDS ISHIHARA SANGYO KAISHA, LTD. (JP) 2011-09-21 EP claimed
WO-2010067895-A1 HERBICIDAL COMPOSITIONS CONTAINING BENZOYLPYRAZOLE COMPOUNDS ISHIHARA SANGYO KAISHA, LTD. (JP) 2010-06-17 WO claimed
US-20100099563-A1 HERBICIDAL COMPOSITIONS CONTAINING BENZOYLPYRAZOLE COMPOUNDS ISHIHARA SANGYO KAISHA, LTD. (JP) 2010-04-22 US claimed
EP-2106697-A1 HERBICIDAL COMPOSITIONS CONTAINING BENZOYLPYRAZOLE COMPOUNDS ISHIHARA SANGYO KAISHA, LTD. (JP) 2009-10-07 EP claimed
US-20260007131-A1 HERBICIDAL COMPOSITION CONTAINING DIFLUOROBUTENOIC ACID AMIDE COMPOUND ISHIHARA SANGYO KAISHA, LTD. (JP) 2026-01-08 US disclosed
US-20250380696-A1 METHOD FOR CONTROLLING UNDESIRED PLANTS AND PROMOTING GROWTH OF USEFUL PLANTS ISHIHARA SANGYO KAISHA, LTD. (JP) 2025-12-18 US disclosed
EP-4552496-A1 HERBICIDAL COMPOSITION CONTAINING DIFLUOROBUTENE ACID AMIDE COMPOUND Ishihara Sangyo Kaisha, Ltd. (JP) 2025-05-14 EP disclosed
US-12239133-B2 Herbicidal composition ISHIHARA SANGYO KAISHA, LTD. (JP) 2025-03-04 US disclosed
US-12096773-B2 Herbicidal composition ISHIHARA SANGYO KAISHA, LTD. (JP) 2024-09-24 US disclosed
US-5998334-A Pyrazole compounds, processes for their production and herbicides containing them ISHIHARA SANGYO KAISHA LTD. (JP) 1999-12-07 US disclosed
EP-0900205-A1 PYRAZOLE COMPOUNDS, PROCESSES FOR THEIR PRODUCTION AND HERBICIDES CONTAINING THEM ISHIHARA SANGYO KAISHA, LTD. (JP) 1999-03-10 EP disclosed
US-5869428-A CONTROLLING WEEDS ISHIHARA SANGYO KAISHA LTD. (JP) 1999-02-09 US disclosed
WO-1997041106-A1 PYRAZOLE COMPOUNDS, PROCESSES FOR THEIR PRODUCTION AND HERBICIDES CONTAINING THEM ISHIHARA SANGYO KAISHA LTD. (JP) 1997-11-06 WO disclosed
EP-0733629-A1 Pyridonesulfonylurea compounds, process for their production and herbicides containing them ISHIHARA SANGYO KAISHA, LTD. (JP) 1996-09-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110263427-A1 HERBICIDAL COMPOSITIONS CONTAINING BENZOYLPYRAZOLE COMPOUNDS HDHD5, CBR3, WEE1 HNF4A 2665/4885KDM4E 1458/4885TDP1 3801/4885
US-20260007131-A1 HERBICIDAL COMPOSITION CONTAINING DIFLUOROBUTENOIC ACID AMIDE COMPOUND DDT, CBR1, DHCR24 HNF4A 1279/4885KDM4E 2388/4885TDP1 2254/4885
US-20100099563-A1 HERBICIDAL COMPOSITIONS CONTAINING BENZOYLPYRAZOLE COMPOUNDS HCN3, CBR3, DDT HNF4A 3537/4885KDM4E 1476/4885TDP1 3789/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.