SCHEMBL7751865

SCHEMBL7751865

Nc1c(C(=O)O)cccc1-c1ncccn1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NAPRT Q6XQN6 2/20 0.55
G6PD P11413 1/20 0.52
CASP7 P55210 1/20 0.52
CASP6 P55212 1/20 0.52
KDM4E B2RXH2 2/20 0.48
TDP1 Q9NUW8 1/20 0.48
ALDH1A1 P00352 6/20 0.47
MAPT P10636 3/20 0.47
ALOX15 P16050 2/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
CYP3A4 P08684 1/20 0.47
TSHR P16473 1/20 0.47
BLM P54132 1/20 0.47
AGER Q15109 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
LMNA P02545 4/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
MYC P01106 2/20 0.43
HSD17B10 Q99714 1/20 0.43
HAVCR2 Q8TDQ0 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15477778 0.86 G6PD (0.49) NAPRTG6PDCASP7CASP6KDM4E
SCHEMBL1535154 0.86 PARP1 (0.50) NAPRTKDM4EALDH1A1MAPTL3MBTL1
SCHEMBL9851131 0.82 G6PD (0.65) NAPRTG6PDCASP7CASP6KDM4E
SCHEMBL10819139 0.81 NAPRT (0.50) NAPRTG6PDCASP7CASP6KDM4E
SCHEMBL465563 0.81 KDM4E (0.55) NAPRTKDM4ETDP1ALDH1A1MAPT
SCHEMBL14958507 0.80 GABRG2 (0.43) NAPRTL3MBTL1LMNAPOLBKMT2A
SCHEMBL8102349 0.80 KDM4E (0.50) NAPRTKDM4ETDP1ALDH1A1MAPT
SCHEMBL435474 0.80 HNF4A (0.59) NAPRTKDM4ETDP1ALDH1A1MAPT
SCHEMBL28455317 0.80 KDM4E (0.50) NAPRTKDM4ETDP1ALDH1A1MAPT
SCHEMBL17744802 0.79 G6PD (0.61) NAPRTG6PDCASP7CASP6KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100413848-C Acylsulfamoylbenzamides, crop protection compositions containing them and processes for their preparation HOECHST SCHERING AGREVO GMBH (DE) 2008-08-27 CN claimed
CN-101668419-B AHAS mutants BASF PLANT SCIENCE GMBH (DE) 2016-03-23 CN disclosed
CN-104903303-A Fused oxazole compounds and use thereof for pest control SUMITOMO CHEMICAL CO 2015-09-09 CN disclosed
CN-104854102-A Pyrone compounds and herbicides comprising same SUMITOMO CHEMICAL CO 2015-08-19 CN disclosed
CN-103180291-B Alkoxyimino derivative and pest control agent KUMIAI CHEMICAL INDUSTRY CO.,LTD. (JP) 2015-08-19 CN disclosed
CN-104797567-A Dihydropyrone compound and herbicide containing the same SUMITOMO CHEMICAL CO 2015-07-22 CN disclosed
CN-102822350-B Polynucleotide molecules for gene regulation in plants MONSANTO TECHNOLOGY LLC 2015-05-06 CN disclosed
CN-104350039-A Alkylphenylsulfide derivative and pest control agent KUMIAI CHEMICAL INDUSTRY CO 2015-02-11 CN disclosed
CN-104263729-A Protein Production In Microorganisms Of The Phylum Labyrinthulomycota MARTEK BIOSCIENCES CORP 2015-01-07 CN disclosed
CN-102414195-B Fused heterocyclic compound and use thereof SUMITOMO CHEMICAL CO 2014-11-12 CN disclosed
CN-102648207-A Production of proteins in microorganisms of the phylum Gliocladium MARTEK BIOSCIENCES CORP 2012-08-22 CN disclosed
CN-102421759-A Pyridazinone compounds and use thereof SUMITOMO CHEMICAL CO 2012-04-18 CN disclosed
CN-102414195-A Fused heterocyclic compound and use thereof SUMITOMO CHEMICAL CO 2012-04-11 CN disclosed
CN-102395550-A Process and composition for preparing low-foam, non-gelling surfactants AKZO NOBEL CHEMICALS INTERNAT 2012-03-28 CN disclosed
CN-101918387-A Alpha, beta-unsaturated imidate compound and pesticidal composition containing the same SUMITOMO CHEMICAL CO 2010-12-15 CN disclosed
CN-101808986-A Imidate compound and use thereof for pest control SUMITOMO CHEMICAL CO 2010-08-18 CN disclosed
CN-100413848-C Acylsulfamoylbenzamides, crop protection compositions containing them and processes for their preparation HOECHST SCHERING AGREVO GMBH (DE) 2008-08-27 CN disclosed
CN-101208280-A Fertilizer-compatible composition BAYER CROPSCIENCE LP (US) 2008-06-25 CN disclosed
EP-1070085-A1 DUAL A v?b 3? AND METASTASIS-ASSOCIATED RECEPTOR LIGANDS G.D. SEARLE & CO. (US) 2001-01-24 EP disclosed
WO-1999051638-A1 DUAL Avb3 AND METASTASIS-ASSOCIATED RECEPTOR LIGANDS G.D. SEARLE & CO. (US) 1999-10-14 WO disclosed