Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 11/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 11/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 11/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 11/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 11/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 11/20 | 0.44 |
| ▸ | GABRA6 | Q16445 | 11/20 | 0.44 |
| ▸ | GABRA4 | P48169 | 10/20 | 0.44 |
| ▸ | GABRP | O00591 | 9/20 | 0.44 |
| ▸ | GABRD | O14764 | 9/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 9/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 9/20 | 0.44 |
| ▸ | GABRE | P78334 | 9/20 | 0.44 |
| ▸ | GABRG1 | Q8N1C3 | 9/20 | 0.44 |
| ▸ | GABRG3 | Q99928 | 9/20 | 0.44 |
| ▸ | GABRQ | Q9UN88 | 9/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26687778 | 0.92 | GABRA1 (0.56) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL13933199 | 0.90 | MEN1 (0.44) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL4348979 | 0.76 | GABRA1 (0.35) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL6748692 | 0.76 | GABRP (0.35) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL20478197 | 0.75 | NQO1 (0.35) | — | |
| SCHEMBL50701 | 0.75 | NQO1 (0.35) | — | |
| SCHEMBL15067231 | 0.74 | NQO1 (0.33) | — | |
| SCHEMBL4349435 | 0.73 | MAPT (0.38) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL13027903 | 0.72 | ESR1 (0.32) | — | |
| SCHEMBL30018330 | 0.71 | ALDH1A1 (0.45) | KDM4EALDH1A1MAPTKMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090054649-A1 | Bridged Organosilane and Production Method Thereof | KABUSHIKI KAISHA TOYOTA CHUO KENKYUSHO (JP) | 2009-02-26 | — | — | US | disclosed |
| US-20090054649-A1 | Bridged Organosilane and Production Method Thereof | KABUSHIKI KAISHA TOYOTA CHUO KENKYUSHO (JP) | 2009-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090054649-A1 | Bridged Organosilane and Production Method Thereof | C5, CCNE1, QSOX1 | GABRA1 4171/4885GABRG2 4062/4885GABRB3 4649/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.