Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TRPC3 | Q13507 | 2/20 | 0.38 |
| ▸ | TRPC7 | Q9HCX4 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4350085 | 0.91 | SMN1; SMN2 (0.41) | KMT2ASMN1; SMN2NPC1RAB9ACYP2C19 | |
| SCHEMBL4533655 | 0.89 | SMN1; SMN2 (0.47) | KMT2ASMN1; SMN2NPC1RAB9ACYP2C19 | |
| SCHEMBL4355143 | 0.88 | GPR119 (0.46) | KMT2ASMN1; SMN2NPC1RAB9ACYP2C19 | |
| SCHEMBL4355710 | 0.88 | KMT2A (0.47) | KMT2ASMN1; SMN2ACHEHPGDGRM5 | |
| SCHEMBL4352115 | 0.86 | GPR119 (0.46) | KMT2ASMN1; SMN2NPC1RAB9ACYP2C19 | |
| SCHEMBL4526460 | 0.85 | SMN1; SMN2 (0.43) | KMT2ASMN1; SMN2NPC1RAB9ACYP2C19 | |
| SCHEMBL4351624 | 0.85 | ENPP2 (0.44) | KMT2ASMN1; SMN2NPC1RAB9ACYP2C19 | |
| SCHEMBL4356808 | 0.83 | SETD7 (0.45) | KMT2ACYP2C19GPR119HPGDMEN1 | |
| SCHEMBL4355595 | 0.82 | POLB (0.54) | SMN1; SMN2ACHECYP2C19HPGDGRM5 | |
| SCHEMBL4520212 | 0.82 | PTPN2 (0.47) | KMT2ASMN1; SMN2CYP2C19HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |