Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Tetradecane. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB known ✓ | P10828 | 1/20 | 0.89 |
| ▸ | MEN1 known ✓ | O00255 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 5/20 | 0.89 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | DNM1 | Q05193 | 6/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Decane SCHEMBL10420748 | 1.00 | TSHR (0.89) | TSHRTHRBLMNADNM1ALDH1A1 | |
| Heptane SCHEMBL3417507 | 1.00 | TSHR (0.89) | TSHRTHRBLMNADNM1ALDH1A1 | |
| Heptane SCHEMBL1143764 | 1.00 | TSHR (0.89) | TSHRTHRBLMNADNM1ALDH1A1 | |
| Octane SCHEMBL9716479 | 1.00 | TSHR (0.89) | TSHRTHRBLMNADNM1ALDH1A1 | |
| Octane SCHEMBL9716483 | 1.00 | TSHR (0.89) | TSHRTHRBLMNADNM1ALDH1A1 | |
| Heptane SCHEMBL21802129 | 1.00 | TSHR (0.89) | TSHRTHRBLMNADNM1ALDH1A1 | |
| Water SCHEMBL4410904 | 1.00 | TSHR (0.89) | TSHRTHRBLMNADNM1ALDH1A1 | |
| Nonane SCHEMBL9836650 | 1.00 | TSHR (0.89) | TSHRTHRBLMNADNM1ALDH1A1 | |
| Decane SCHEMBL9735848 | 1.00 | TSHR (0.89) | TSHRTHRBLMNADNM1ALDH1A1 | |
| Dodecane SCHEMBL6340877 | 1.00 | TSHR (0.89) | TSHRTHRBLMNADNM1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107805261-A | A kind of self assembly quaternary phosphine salt material | 南京大学（苏州）高新技术研究院 | 2018-03-16 | — | — | CN | claimed |
| CN-107715918-A | A kind of heterogeneous catalysis and the method for cyclic carbonate ester is prepared using it | 江苏苏博特新材料股份有限公司 | 2018-02-23 | — | — | CN | claimed |
| CN-110352071-A | Lipidic nanoparticles mRNA vaccine | 库瑞瓦格股份公司 | 2019-10-18 | — | — | CN | disclosed |
| CN-107250271-B | Polyether polymer composition | 日本瑞翁株式会社 | 2019-06-11 | — | — | CN | disclosed |
| CN-109321236-A | A kind of quantum dot and the preparation method and application thereof | TCL集团股份有限公司 | 2019-02-12 | — | — | CN | disclosed |
| CN-108218909-A | For the compound based on the adduct with isocyanates of coating composition | 赢创德固赛有限公司 | 2018-06-29 | — | — | CN | disclosed |
| CN-107805261-A | A kind of self assembly quaternary phosphine salt material | 南京大学（苏州）高新技术研究院 | 2018-03-16 | — | — | CN | disclosed |
| CN-104844665-B | A kind of Kdo of the low toxicity containing five fatty acid chains2The preparation and application of MPLA | 江南大学 | 2018-03-16 | — | — | CN | disclosed |
| CN-107250271-A | Polyether polymer composition | 日本瑞翁株式会社 | 2017-10-13 | — | — | CN | disclosed |
| CN-107073100-A | FMDV recombinant vaccines and application thereof | 梅里亚股份有限公司 | 2017-08-18 | — | — | CN | disclosed |
| CN-104684998-B | Method for producing rubber composition | 日本瑞翁株式会社 | 2017-04-12 | — | — | CN | disclosed |
| CN-101291995-A | Water-absorbing agent having water-absorbent resin as main component and method for producing the water-absorbing agent | NIPPON CATALYTIC CHEM IND (JP) | 2008-10-22 | — | — | CN | disclosed |
| EP-1928956-A1 | WATER-ABSORBING AGENT HAVING WATER-ABSORBENT RESIN AS A MAIN COMPONENT AND PRODUCTION METHOD OF THE WATER-ABSORBING AGENT | Nippon Shokubai Co., Ltd. (JP) | 2008-06-11 | — | — | EP | disclosed |
| WO-2007037454-A9 | WATER-ABSORBING AGENT HAVING WATER-ABSORBENT RESIN AS A MAIN COMPONENT AND PRODUCTION METHOD OF THE WATER-ABSORBING AGENT | NIPPON CATALYTIC CHEM IND (JP) | 2007-05-24 | — | — | WO | disclosed |
| WO-2007037454-A1 | WATER-ABSORBING AGENT HAVING WATER-ABSORBENT RESIN AS A MAIN COMPONENT AND PRODUCTION METHOD OF THE WATER-ABSORBING AGENT | NIPPON SHOKUBAI CO., LTD. (JP) | 2007-04-05 | — | — | WO | disclosed |
| CN-1176936-C | Carbamycin derivatives and pharmaceutical compositions containing the same | ������������ʽ���� | 2004-11-24 | — | — | CN | disclosed |
| CN-1450394-A | Optical alignment method and liquid crystal display element | JSR CORP (JP) | 2003-10-22 | — | — | CN | disclosed |
| CN-1382152-A | Novel A-500359 derivatives | SANKYO CO (JP) | 2002-11-27 | — | — | CN | disclosed |
| CN-1032863-C | Copolymer compositions comprising copolymer and one or more lybricating additives | SHELL INT RESEARCH (NL) | 1996-09-25 | — | — | CN | disclosed |
| CN-1055375-A | The copolymer compositions that contains multipolymer and one or more slip additives | SHELL INT RESEARCH (NL) | 1991-10-16 | — | — | CN | disclosed |