SCHEMBL2589620

SCHEMBL2589620

O=C(O)CCC(=O)ON1C(=O)CCC1=O.OCC(CO)(CO)CO

nearest known ligand 0.34

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PSMB8 P28062 1/20 0.34
PSMB5 P28074 1/20 0.34
KDM6B O15054 1/20 0.31
KDM5C P41229 1/20 0.31
EGLN1 Q9GZT9 1/20 0.31
PHF8 Q9UPP1 1/20 0.31
KDM2A Q9Y2K7 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5223031 0.91 PSMB8 (0.34) PSMB8PSMB5KDM6BKDM5CEGLN1
SCHEMBL2593469 0.91 TSHR (0.37) PSMB8PSMB5
SCHEMBL43575 0.90 EGLN1 (0.36) PSMB8PSMB5KDM6BKDM5CEGLN1
Ethylene Glycol SCHEMBL2467342 0.88 PSMB8 (0.35) PSMB8PSMB5KDM6BKDM5CEGLN1
Methoxymethane SCHEMBL7956362 0.85 EGLN1 (0.37) PSMB8PSMB5KDM6BKDM5CEGLN1
Urea SCHEMBL4909809 0.84 PSMB8 (0.34) PSMB8PSMB5KDM6BKDM5CEGLN1
Propionic Acid SCHEMBL29510501 0.83 EGLN1 (0.36) PSMB8PSMB5KDM6BKDM5CEGLN1
Sulfuric Acid SCHEMBL12813397 0.83 PARL (0.35) PSMB8PSMB5KDM6BKDM5CEGLN1
SCHEMBL31121824 0.83 LMNA (0.36) PSMB8PSMB5KDM6BKDM5CEGLN1
SCHEMBL2589615 0.83 ALDH1A1 (0.32) PSMB8PSMB5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190263750-A1 IN VIVO GELLING PHARMACEUTICAL PRE-FORMULATION THERAGENICS CORPORATION 2019-08-29 US claimed
US-10189773-B2 In-vivo gelling pharmaceutical pre-formulation MEDICUS BIOSCIENCES, LLC (US) 2019-01-29 US claimed
EP-2846847-A1 BIOCOMPATIBLE HYDROGEL TREATMENTS FOR RETINAL DETACHMENT Medicus Biosciences LLC (US) 2015-03-18 EP claimed
CN-104428014-A Biocompatible hydrogel treatment for retinal detachment MEDICUS BIOSCIENCES LLC 2015-03-18 CN claimed
WO-2013170195-A1 BIOCOMPATIBLE HYDROGEL TREATMENTS FOR RETINAL DETACHMENT MEDICUS BIOSCIENCES, LLC (US) 2013-11-14 WO claimed
US-20130116341-A1 IN-VIVO GELLING PHARMACEUTICAL PRE-FORMULATION MEDICUS BIOSCIENCES, LLC (US) 2013-05-09 US claimed
CN-101056595-B Compositions, systems and methods for treatment of defects in blood vessels MICROVENTION, INC. (US) 2012-02-08 CN claimed
WO-2011140519-A2 IN VIVO GELLING PHARMACEUTICAL PRE-FORMULATION MEDICUS BIOSCIENCES, LLC (US) 2011-11-10 WO claimed
CN-101056595-A Compositions, systems and methods for treatment of defects in blood vessels MICROVENTION INC (US) 2007-10-17 CN claimed
EP-1824414-A2 COMPOSITIONS, SYSTEMS AND METHODS FOR TREATMENT OF DEFECTS IN BLOOD VESSELS MicroVention, Inc. (US) 2007-08-29 EP claimed
US-7201918-B2 Compositions, systems and methods for treatment of defects in blood vessels MICROVENTION, INC. (US) 2007-04-10 US claimed
WO-2006055690-A2 COMPOSITIONS, SYSTEMS AND METHODS FOR TREATMENT OF DEFECTS IN BLOOD VESSELS MICROVENTION, INC. (US) 2006-05-26 WO claimed
US-20060105014-A1 Compositions, systems and methods for treatment of defects in blood vessels MICROVENTION, INC. (US) 2006-05-18 US claimed
US-20230218799-A1 BIOCOMPATIBLE HYDROGEL TREATMENTS FOR RETINAL DETACHMENT AQUARIAN CREDIT FUNDING LLC 2023-07-13 US disclosed
EP-2968680-B1 SOLID POLYGLYCOL-BASED BIOCOMPATIBLE PRE-FORMULATION C P MEDICAL CORP (US) 2023-05-03 EP disclosed
US-11596710-B2 Biocompatible hydrogel treatments for retinal detachment AQUARIAN CREDIT FUNDING LLC 2023-03-07 US disclosed
EP-1824414-A2 COMPOSITIONS, SYSTEMS AND METHODS FOR TREATMENT OF DEFECTS IN BLOOD VESSELS MicroVention, Inc. (US) 2007-08-29 EP disclosed
US-7201918-B2 Compositions, systems and methods for treatment of defects in blood vessels MICROVENTION, INC. (US) 2007-04-10 US disclosed
WO-2006055690-A2 COMPOSITIONS, SYSTEMS AND METHODS FOR TREATMENT OF DEFECTS IN BLOOD VESSELS MICROVENTION, INC. (US) 2006-05-26 WO disclosed
US-20060105014-A1 Compositions, systems and methods for treatment of defects in blood vessels MICROVENTION, INC. (US) 2006-05-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10189773-B2 In-vivo gelling pharmaceutical pre-formulation FURIN, ARFGAP1, MGST1 PSMB8 1695/4885PSMB5 2319/4885KDM6B 3872/4885
US-20230218799-A1 BIOCOMPATIBLE HYDROGEL TREATMENTS FOR RETINAL DETACHMENT ALDH1A2, RB1, UACA PSMB8 2250/4885PSMB5 2255/4885KDM6B 1260/4885
US-11596710-B2 Biocompatible hydrogel treatments for retinal detachment ALDH1A2, RB1, UACA PSMB8 2250/4885PSMB5 2255/4885KDM6B 1260/4885
US-20190263750-A1 IN VIVO GELLING PHARMACEUTICAL PRE-FORMULATION FURIN, ARFGAP1, MGST1 PSMB8 1715/4885PSMB5 2559/4885KDM6B 4054/4885
US-20130116341-A1 IN-VIVO GELLING PHARMACEUTICAL PRE-FORMULATION FURIN, ARFGAP1, MGST1 PSMB8 1695/4885PSMB5 2319/4885KDM6B 3872/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.