Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.58 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.48 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL435532 | 0.91 | TDP1 (0.72) | TDP1ALOX5POLBAPEX1HTT | |
| SCHEMBL8023503 | 0.88 | HDAC1 (0.49) | TDP1ALOX5HDAC3HDAC4HDAC1 | |
| SCHEMBL148938 | 0.88 | LMNA (0.60) | TDP1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL146245 | 0.86 | POLB (0.55) | TDP1SMN1; SMN2POLBAPEX1HTT | |
| Lithium SCHEMBL30708617 | 0.86 | LMNA (0.58) | TDP1SMN1; SMN2POLBAPEX1HTT | |
| SCHEMBL11887997 | 0.85 | TDP1 (0.54) | TDP1ALOX5SMN1; SMN2MAPK1SLC6A3 | |
| SCHEMBL4447342 | 0.85 | POLB (0.57) | TDP1SMN1; SMN2POLBAPEX1HTT | |
| SCHEMBL232155 | 0.85 | POLB (0.57) | TDP1SMN1; SMN2POLBAPEX1HTT | |
| SCHEMBL233287 | 0.85 | POLB (0.57) | TDP1SMN1; SMN2POLBAPEX1HTT | |
| SCHEMBL1562514 | 0.85 | POLB (0.57) | TDP1SMN1; SMN2POLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012010918-A2 | OPTICAL DEVICES | MEDICONTUR ORVOSTECHNIKAI KFT. (HU) | 2012-01-26 | — | — | WO | disclosed |