Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | ABL1 | P00519 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | PKM | P14618 | 1/20 | 0.64 |
| ▸ | IDE | P14735 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | CA12 | O43570 | 6/20 | 0.47 |
| ▸ | CA1 | P00915 | 6/20 | 0.47 |
| ▸ | CA2 | P00918 | 6/20 | 0.47 |
| ▸ | CA9 | Q16790 | 6/20 | 0.47 |
| ▸ | HLCS | P50747 | 4/20 | 0.47 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL318637 | 0.96 | TDP1 (0.61) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL3870139 | 0.84 | TDP1 (0.61) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL10002269 | 0.84 | TDP1 (0.67) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL13888577 | 0.84 | TDP1 (0.67) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL1727527 | 0.84 | TDP1 (0.67) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL318962 | 0.83 | TDP1 (0.53) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL5903549 | 0.83 | TDP1 (0.48) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL140972 | 0.82 | TDP1 (0.72) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL31224941 | 0.82 | TDP1 (0.72) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL14165464 | 0.82 | TDP1 (0.72) | TDP1MEN1ABL1LMNAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1684810-A4 | POLYBIOTIN COMPOUNDS FOR MAGNETIC RESONANCE IMAGINING AND DRUG DELIVERY | GEN HOSPITAL CORP (US) | 2009-05-27 | — | — | EP | disclosed |
| EP-1684810-A1 | POLYBIOTIN COMPOUNDS FOR MAGNETIC RESONANCE IMAGINING AND DRUG DELIVERY | THE GENERAL HOSPITAL CORPORATION (US) | 2006-08-02 | — | — | EP | disclosed |
| WO-2005032598-A1 | POLYBIOTIN COMPOUNDS FOR MAGNETIC RESONANCE IMAGINING AND DRUG DELIVERY | THE GENERAL HOSPITAL CORPORATION (US) | 2005-04-14 | — | — | WO | disclosed |