Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL436179 | 0.87 | GRIA2 (0.35) | GHSROPRM1OPRD1OPRK1 | |
| SCHEMBL435891 | 0.80 | FAAH (0.36) | OPRM1OPRD1OPRK1 | |
| SCHEMBL436428 | 0.79 | RAF1 (0.32) | GHSRCA1CA2ACHE | |
| SCHEMBL346598 | 0.78 | KHK (0.40) | GHSR | |
| SCHEMBL436765 | 0.78 | ALDH1A1 (0.39) | — | |
| SCHEMBL436429 | 0.76 | GHSR (0.35) | GHSROPRM1OPRD1OPRK1CA1 | |
| SCHEMBL346900 | 0.74 | GHSR (0.46) | GHSRCA1CA2ACHE | |
| SCHEMBL436766 | 0.74 | NR1H2 (0.39) | OPRM1OPRD1OPRK1 | |
| SCHEMBL435693 | 0.74 | SSTR4 (0.33) | GHSR | |
| SCHEMBL345716 | 0.74 | KHK (0.40) | GHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012012320-A1 | SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF | MILLENIUM PHARMACEUTICALS, INC. (US) | 2012-01-26 | — | — | WO | disclosed |