Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.47 |
| ▸ | RXRA | P19793 | 2/20 | 0.42 |
| ▸ | RXRB | P28702 | 2/20 | 0.42 |
| ▸ | RXRG | P48443 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5744413 | 0.78 | GABRA5 (0.49) | FFAR4ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL3641902 | 0.76 | FFAR4 (0.50) | FFAR4ALDH1A1GPBAR1PTGS2 | |
| SCHEMBL1779686 | 0.75 | BRD4 (0.42) | ALDH1A1SMN1; SMN2HPGDKDM4EGAA | |
| SCHEMBL4723502 | 0.75 | ALDH1A1 (0.56) | ALDH1A1KDM4EGAAMAPTMEN1 | |
| SCHEMBL3642881 | 0.74 | FFAR4 (0.50) | FFAR4MAPTMEN1KMT2APTGS1 | |
| SCHEMBL4720867 | 0.73 | FFAR4 (0.42) | FFAR4GPBAR1CYP1A2CYP1A1CYP2E1 | |
| SCHEMBL4974872 | 0.72 | PTGS2 (0.58) | FFAR4ALDH1A1KDM4EGAAMEN1 | |
| SCHEMBL11473576 | 0.72 | GAA (0.43) | ALDH1A1SMN1; SMN2HPGDKDM4ELMNA | |
| SCHEMBL31526337 | 0.71 | PTGS1 (0.47) | FFAR4ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL4764778 | 0.70 | ALDH1A1 (0.40) | FFAR4ALDH1A1MEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2595985-A1 | ISOXAZOLE, ISOTHIAZOLE, FURANE AND THIOPHENE COMPOUNDS AS MICROBICIDES | Syngenta Participations AG (CH) | 2013-05-29 | — | — | EP | disclosed |
| WO-2012010567-A1 | ISOXAZOLE, ISOTHIAZOLE, FURANE AND THIOPHENE COMPOUNDS AS MICROBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-01-26 | — | — | WO | disclosed |