Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 10/20 | 0.39 |
| ▸ | EIF2AK3 | Q9NZJ5 | 2/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 8/20 | 0.39 |
| ▸ | ABL1 | P00519 | 8/20 | 0.39 |
| ▸ | EGFR | P00533 | 8/20 | 0.39 |
| ▸ | HCK | P08631 | 8/20 | 0.39 |
| ▸ | KDR | P35968 | 8/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 8/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 8/20 | 0.39 |
| ▸ | MTOR | P42345 | 8/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 8/20 | 0.39 |
| ▸ | EPHB4 | P54760 | 8/20 | 0.39 |
| ▸ | PRKDC | P78527 | 8/20 | 0.39 |
| ▸ | PI4KB | Q9UBF8 | 7/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1128311 | 0.79 | GPR119 (0.48) | NR3C1CYP2C9 | |
| Hydrochloric Acid SCHEMBL1128930 | 0.78 | CYP3A4 (0.41) | SRCEIF2AK3ABL1HTR1ASLC6A2 | |
| SCHEMBL1128995 | 0.75 | CYP3A4 (0.48) | FGFR1SRCEIF2AK3NR3C1LCK | |
| SCHEMBL24196837 | 0.75 | SRC (0.54) | FGFR1SRCPIK3CDABL1EGFR | |
| SCHEMBL4359027 | 0.68 | CYP3A4 (0.38) | CYP3A4CYP2C9 | |
| SCHEMBL24251925 | 0.68 | SRC (0.57) | FGFR1SRCPIK3CDABL1EGFR | |
| SCHEMBL31693325 | 0.66 | JAK2 (0.40) | FGFR1SRCPIK3CDABL1EGFR | |
| SCHEMBL31693335 | 0.66 | JAK2 (0.40) | FGFR1SRCPIK3CDABL1EGFR | |
| SCHEMBL27834954 | 0.66 | NR3C1 (0.45) | FGFR1SRCEIF2AK3PIK3CDABL1 | |
| SCHEMBL24196618 | 0.65 | BTK (0.63) | SRCPIK3CDABL1EGFRHCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8188098-B2 | GPR119 receptor agonists | HOFFMANN-LA ROCHE INC. (US) | 2012-05-29 | — | — | US | disclosed |
| US-20090286812-A1 | GPR119 Receptor Agonists | ERICKSON SHAWN DAVID | 2009-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090286812-A1 | GPR119 Receptor Agonists | GPR119, GPR27, GPR139 | FGFR1 458/4885SRC 2944/4885EIF2AK3 3012/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.