Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | CTSD | P07339 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | ALPL | P05186 | 1/20 | 0.51 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10613860 | 0.84 | ALDH1A1 (0.68) | ALDH1A1CTSDCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL975117 | 0.84 | ALDH1A1 (0.68) | ALDH1A1CTSDCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL29696138 | 0.83 | TSHR (0.67) | ALDH1A1CTSDCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL30727560 | 0.83 | TSHR (0.67) | ALDH1A1CTSDCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL78205 | 0.83 | TSHR (0.67) | ALDH1A1CTSDCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4078013 | 0.82 | ALDH1A1 (0.64) | ALDH1A1CTSDCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7437947 | 0.82 | GPR35 (0.58) | ALDH1A1CTSDCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL6971514 | 0.82 | ALDH1A1 (0.76) | ALDH1A1CTSDCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7900372 | 0.81 | ALDH1A1 (0.63) | ALDH1A1CTSDCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL334763 | 0.81 | ALDH1A1 (0.63) | ALDH1A1CTSDCYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 154 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2697206-B1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF IN THE TREATMENT OF SEXUAL DISORDERS | ATIR HOLDING S A (LU) | 2019-04-03 | — | — | EP | claimed |
| EP-3064489-A1 | ARYLOYL(OXY OR AMINO)PENTAFLUOROSULFANYLBENZENE COMPOUND, PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, AND PRODRUGS THEREOF | Ube Industries, Ltd. (JP) | 2016-09-07 | — | — | EP | claimed |
| US-20160244407-A1 | ARYLOYL(OXY OR AMINO)PENTAFLUOROSULFANYLBENZENE COMPOUND, PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, AND PRODRUGS THEREOF | UBE INDUSTRIES, LTD. (JP) | 2016-08-25 | — | — | US | claimed |
| US-20160185743-A1 | 15-Oxospiramilactone Derivatives, Preparation Method and Uses Thereof | CENTER FOR EXCELLENCE IN MOLECULAR CELL SCIENCE, CHINESE ACADEMY OF SCIENCES (CN) | 2016-06-30 | — | — | US | claimed |
| EP-1934243-A1 | RING-CLOSING METATHESIS PROCESS FOR THE PREPARATION OF MACROCYCLIC PEPTIDES | Boehringer Ingelheim International GmbH (DE) | 2008-06-25 | — | — | EP | claimed |
| WO-2007030656-A1 | RING-CLOSING METATHESIS PROCESS FOR THE PREPARATION OF MACROCYCLIC PEPTIDES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-03-15 | — | — | WO | claimed |
| EP-0836592-A1 | AZEPANES AND THEIR RING HOMOLOGUES FOR THERAPY AND PROPHYLAXIS OF PROTEIN KINASE MEDIATED DISEASES | F. HOFFMANN-LA ROCHE AG (CH) | 1998-04-22 | — | — | EP | claimed |
| WO-1997002249-A1 | NOVEL AZEPANES AND THEIR RING HOMOLOGUES FOR THERAPY AND PROPHYLAXIS OF PROTEIN KINASE MEDIATED DISEASES | F. HOFFMANN-LA ROCHE AG (CH) | 1997-01-23 | — | — | WO | claimed |
| US-5196437-A | Macrolide | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1993-03-23 | — | — | US | claimed |
| EP-0196026-B1 | FUNCTIONAL DERIVATIVES OF PHOSPHORUS CONTAINING ACETIC ACIDS, PROCESS FOR THEIR PREPARATION AND HERBICIDAL AND PLANT GROWTH REGULATOR COMPOSITION CONTAINING THEM | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-05-31 | — | — | EP | claimed |
| EP-0237964-A2 | 2-Azolylmethyl-2-aryl-1,3-dioxolanes and their salts, processes for their preparation, compositions containing them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-09-23 | — | — | EP | claimed |
| US-4291047-A | Combating fungi with α-azolyl-β-hydroxy-ketones | BAYER AKTIENGESELLSCHAFT (DE) | 1981-09-22 | — | — | US | claimed |
| JP-1246282-A | — | — | None | — | — | JP | disclosed |
| JP-1246283-A | — | — | None | — | — | JP | disclosed |
| JP-10218888-A | — | — | None | — | — | JP | disclosed |
| EP-4301398-A1 | URIDINE PHOSPHORYLASE INHIBITORS TO PREVENT OR TREAT DRUG-INDUCED PULMONARY DYSFUNCTION | Tosk, Inc. (US) | 2024-01-10 | — | — | EP | disclosed |
| US-3998999-A | Process for preparing pyrazomycin and pyrazomycin B | HOFFMANN-LA ROCHE INC. (US) | 1976-12-21 | — | — | US | disclosed |
| US-3978063-A | 1,2,3,4-Tetrahydroisoquinoline derivatives and the preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1976-08-31 | — | — | US | disclosed |
| US-3966703-A | Asymmetrical frisazo dyestuffs derived from diazotized 2,7-diamino-carbazole | BAYER AKTIENGESELLSCHAFT (DT) | 1976-06-29 | — | — | US | disclosed |
| US-3963725-A | 1,2,3,4-Tetrahydroisoquinoline derivatives and the preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1976-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160185743-A1 | 15-Oxospiramilactone Derivatives, Preparation Method and Uses Thereof | WNT1, WNT3, WNT3A | ALDH1A1 542/4885CTSD 3668/4885CYP1A2 3003/4885 |
| US-20160244407-A1 | ARYLOYL(OXY OR AMINO)PENTAFLUOROSULFANYLBENZENE COMPOUND, PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, AND PRODRUGS THEREOF | SLCO1B1, SLCO2B1, SLCO1B3 | ALDH1A1 414/4885CTSD 2903/4885CYP1A2 85/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.