Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | ADRA1D | P25100 | 6/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 6/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 6/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR7 | P34969 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LDHA | P00338 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4364652 | 1.00 | PKM (0.48) | PKMADRA1DADRA1AADRA1BADRB2 | |
| SCHEMBL27968675 | 0.84 | LDHA (0.57) | ALDH1A1LDHAHTTALOX15ALOX12 | |
| Hydrochloric Acid SCHEMBL9634032 | 0.81 | ADRA1D (0.52) | PKMADRA1DADRA1AADRA1BADRB2 | |
| SCHEMBL30254854 | 0.81 | ADRA1D (0.49) | PKMADRA1DADRA1AADRA1BADRB2 | |
| SCHEMBL13623709 | 0.80 | ADRA1D (0.48) | PKMADRA1DADRA1AADRA1BADRB2 | |
| SCHEMBL3948856 | 0.79 | ADRA1D (0.55) | PKMADRA1DADRA1AADRA1BADRB2 | |
| SCHEMBL1412238 | 0.79 | ADRA1D (0.55) | PKMADRA1DADRA1AADRA1BADRB2 | |
| SCHEMBL1412240 | 0.79 | ADRA1D (0.55) | PKMADRA1DADRA1AADRA1BADRB2 | |
| SCHEMBL13880696 | 0.79 | ADRA1D (0.55) | PKMADRA1DADRA1AADRA1BADRB2 | |
| SCHEMBL29519545 | 0.79 | ADRA1D (0.55) | PKMADRA1DADRA1AADRA1BADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7619116-B2 | Intermediates for the synthesis of (R)-tamsulosin and of its pharmaceutically acceptable salts and process for their preparation | Products Chimiques Auxiliaires Et de Synthese (FR) | 2009-11-17 | — | — | US | disclosed |
| EP-1697316-B1 | NOVEL INTERMEDIATES FOR THE SYNTHESIS OF (R)-TAMSULOSIN AND OF ITS PHARMACEUTICALLY ACCEPTABLE SALTS AND PROCESS FOR THEIR PREPARATION | PROD CHIM AUXILIAIRES ET DE SY (FR) | 2008-10-08 | — | — | EP | disclosed |
| US-20070106079-A1 | Novel intermediates for the synthesis of (r)-tamsulosin and of its pharmaceutically acceptable salts and process for their preparation | PRODUITS CHIMIQUES AUXILIAIRES ET DE SYNTHESE (FR) | 2007-05-10 | — | — | US | disclosed |
| EP-1697316-A1 | NOVEL INTERMEDIATES FOR THE SYNTHESIS OF (R)-TAMSULOSIN AND OF ITS PHARMACEUTICALLY ACCEPTABLE SALTS AND PROCESS FOR THEIR PREPARATION | PRODUITS CHIMIQUES AUXILIAIRES ET DE SYNTHESE (FR) | 2006-09-06 | — | — | EP | disclosed |
| WO-2005058810-A1 | NOVEL INTERMEDIATES FOR THE SYNTHESIS OF (R)-TAMSULOSIN AND OF ITS PHARMACEUTICALLY ACCEPTABLE SALTS AND PROCESS FOR THEIR PREPARATION | PRODUITS CHIMIQUES AUXILIAIRES ET DE SYNTHESE (FR) | 2005-06-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070106079-A1 | Novel intermediates for the synthesis of (r)-tamsulosin and of its pharmaceutically acceptable salts and process for their preparation | ADRB1, AVPR2, ADRA1A | PKM 476/4885ADRA1D 11/4885ADRA1A 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.