SCHEMBL43657

SCHEMBL43657

O=c1c2cc3c(=O)n(O)c(=O)c3cc2c(=O)n1O

nearest known ligand 0.41

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.41
GAA P10253 2/20 0.41
POLB P06746 1/20 0.41
CA12 O43570 7/20 0.40
CA9 Q16790 7/20 0.40
FEN1 P39748 8/20 0.38
ERCC1 P07992 4/20 0.38
ERCC4 Q92889 4/20 0.38
ERCC5 P28715 2/20 0.38
RNASEH1 O60930 1/20 0.38
ALDH1A1 P00352 3/20 0.36
DNASE1 P24855 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5516639 0.88 CA12 (0.38) KDM4EGAAPOLBCA12CA9
SCHEMBL9361606 0.78
SCHEMBL10758453 0.78 MAPK1 (0.61) KDM4EGAAPOLBCA12CA9
SCHEMBL11761216 0.72 ALDH1A1 (0.32) KDM4EGAACA12CA9FEN1
SCHEMBL12310076 0.67 ALDH1A1 (0.36) KDM4EGAAPOLBCA12CA9
SCHEMBL17789200 0.65 ALDH1A1 (0.44) KDM4EGAAPOLBALDH1A1
SCHEMBL6675514 0.63 CA12 (0.65) KDM4EGAAPOLBCA12CA9
SCHEMBL9550360 0.61 ALDH1A1 (0.32) KDM4EGAAPOLBALDH1A1
SCHEMBL3437734 0.61 ALDH1A1 (0.42) KDM4EGAAPOLBALDH1A1
SCHEMBL12541553 0.61 ALDH1A1 (0.46) KDM4EGAAPOLBCA9ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 677 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119081467-A Anthocyanin temperature-change water-based ink and preparation method thereof 武汉淡雅香生物科技有限公司 2024-12-06 CN claimed
CN-118666654-A Nocardomperidone and process for producing the same 武汉合生科技有限公司 2024-09-20 CN claimed
CN-116444418-B Method for breaking tertiary amine C-N bond by enzyme-like catalytic oxidation 中国科学院青岛生物能源与过程研究所 2024-09-20 CN claimed
CN-116284017-B Method for preparing amide compound by utilizing enzyme-like efficient catalytic oxidation 中国科学院青岛生物能源与过程研究所 2024-03-22 CN claimed
CN-115233319-B One-bath degumming method for flax by selective oxidation and alkali boiling 东华大学 2023-10-20 CN claimed
CN-116444418-A Method for breaking tertiary amine C-N bond by enzyme-like catalytic oxidation 中国科学院青岛生物能源与过程研究所 2023-07-18 CN claimed
CN-116284017-A Method for preparing amide compound by utilizing enzyme-like efficient catalytic oxidation 中国科学院青岛生物能源与过程研究所 2023-06-23 CN claimed
CN-114591222-A Method for efficiently preparing fluoro-alkene amide 江南大学 2022-06-07 CN claimed
US-10160712-B2 Method of catalytic oxidation of lignite using oxygen as oxidant at atmospheric pressure CHINA UNIVERSITY OF MINING AND TECHNOLOGY (CN) 2018-12-25 US claimed
US-20180237371-A1 METHOD OF CATALYTIC OXIDATION OF LIGNITE USING OXYGEN AS OXIDANT AT ATMOSPHERIC PRESSURE CHINA UNIVERSITY OF MINING AND TECHNOLOGY (CN) 2018-08-23 US claimed
EP-2705081-A1 ACTIVATED OXYGEN SCAVENGING COMPOSITIONS FOR PLASTIC CONTAINERS Graham Packaging Company, L.P. (US) 2014-03-12 EP claimed
EP-2507307-B1 USE OF PROTECTED N-HYDROXYIMIDE DERIVATES AND TRANSITION METAL AS OXYGEN SCAVENGER SYSTEM IN TRANSPARENT POLYOLEFIN FILMS BASF SE (DE) 2014-02-12 EP claimed
WO-2012154379-A1 ACTIVATED OXYGEN SCAVENGING COMPOSITIONS FOR PLASTIC CONTAINERS GRAHAM PACKAGING COMPANY, L.P. (US) 2012-11-15 WO claimed
US-20120283366-A1 ACTIVATED OXYGEN SCAVENGING COMPOSITIONS FOR PLASTIC CONTAINERS GRAHAM PACKAGING COMPANY, L.P. (US) 2012-11-08 US claimed
US-8252481-B2 Fuel cell system and solid polymer electrolyte film NISSAN MOTOR CO., LTD. (JP) 2012-08-28 US claimed
US-20110039166-A1 Fuel cell system and solid polymer electrolyte film NISSAN MOTOR CO., LTD. 2011-02-17 US claimed
US-7799485-B2 Fuel cell system and composition for electrode NISSAN MOTOR CO., LTD. (JP) 2010-09-21 US claimed
US-20090233128-A1 FUEL, FUEL CELL SYSTEM, FUEL CELL VEHICLE AND OPERATING METHOD FOR FUEL CELL SYSTEM NISSAN MOTOR CO., LTD. 2009-09-17 US claimed
US-20080050631-A1 Fuel Cell System and Composition for Electrode NISSAN MOTOR CO., LTD. 2008-02-28 US claimed
US-20080044709-A1 Fuel Cell System and Solid Polymer Electrolyte Film NISSAN MOTOR CO., LTD. 2008-02-21 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10160712-B2 Method of catalytic oxidation of lignite using oxygen as oxidant at atmospheric pressure HAO2, EGLN2, CAPN9 KDM4E 666/4885GAA 1719/4885POLB 2976/4885
US-20180237371-A1 METHOD OF CATALYTIC OXIDATION OF LIGNITE USING OXYGEN AS OXIDANT AT ATMOSPHERIC PRESSURE HAO2, ELL, NOX4 KDM4E 396/4885GAA 3145/4885POLB 2305/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.