SCHEMBL4366142

SCHEMBL4366142

CCCCOC(=O)c1ccc[nH]1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 1/20 0.58
MMP1 P03956 1/20 0.57
MMP9 P14780 1/20 0.57
MMP12 P39900 1/20 0.57
TSHR P16473 6/20 0.57
L3MBTL1 Q9Y468 3/20 0.57
TDP1 Q9NUW8 2/20 0.57
MAPK1 P28482 3/20 0.51
CYP3A4 P08684 3/20 0.51
TP53 P04637 1/20 0.51
LMNA P02545 4/20 0.50
ALDH1A1 P00352 3/20 0.50
CYP1A2 P05177 2/20 0.50
CYP2C19 P33261 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
ESR1 P03372 2/20 0.50
HSD17B10 Q99714 1/20 0.50
CYP2D6 P10635 1/20 0.50
NR1H2 P55055 1/20 0.50
RNASEL Q05823 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28002724 0.95 MMP2 (0.65) MMP2MMP1MMP9MMP12TSHR
SCHEMBL9496881 0.90 ALDH1A1 (0.55) MMP2MMP1MMP9MMP12TSHR
SCHEMBL29020282 0.85 RAB9A (0.49) MMP2MMP1MMP9MMP12TSHR
SCHEMBL428389 0.82 RAB9A (0.53) TSHRLMNAALDH1A1CYP1A2SMN1; SMN2
SCHEMBL16353007 0.81 MMP2 (0.44) MMP2MMP1MMP9MMP12TSHR
Hydrochloric Acid SCHEMBL29099350 0.81 RAB9A (0.51) TSHRLMNAALDH1A1CYP1A2SMN1; SMN2
SCHEMBL1170832 0.81 RAB9A (0.51) MMP2TSHRL3MBTL1SMN1; SMN2RAB9A
SCHEMBL28716266 0.81 MMP2 (0.49) MMP2MMP1MMP9MMP12TSHR
SCHEMBL21104219 0.80 RAB9A (0.43) MMP2MMP1MMP9MMP12TSHR
SCHEMBL21104427 0.80 RAB9A (0.43) MMP2MMP1MMP9MMP12TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119265552-A Chemical nickel-plating palladium-gold solution 生益电子股份有限公司 2025-01-07 CN claimed
WO-2023030423-A1 ENVIRONMENTALLY FRIENDLY IMPREGNATION SYSTEM FOR FIBER SURFACE TREATMENT, AND PREPARATION METHOD AND IMPREGNATION TREATMENT METHOD THEREFOR 北京化工大学 2023-03-09 WO claimed
CN-110143907-A A kind of 9,10- dipyrryl anthracene fluorescent chemicals and its preparation method and application 江西科技师范大学 2019-08-20 CN claimed
CN-119265552-A Chemical nickel-plating palladium-gold solution 生益电子股份有限公司 2025-01-07 CN disclosed
CN-115093355-B Preparation method of pyrrole ester compound 河南农业大学 2024-06-04 CN disclosed
WO-2023030423-A1 ENVIRONMENTALLY FRIENDLY IMPREGNATION SYSTEM FOR FIBER SURFACE TREATMENT, AND PREPARATION METHOD AND IMPREGNATION TREATMENT METHOD THEREFOR 北京化工大学 2023-03-09 WO disclosed
CN-115093355-A Preparation method of pyrrole ester compound 河南农业大学 2022-09-23 CN disclosed
WO-2022194269-A1 NOVEL EGFR DEGRADATION AGENT 上海齐鲁制药研究中心有限公司 2022-09-22 WO disclosed
CN-110143907-A A kind of 9,10- dipyrryl anthracene fluorescent chemicals and its preparation method and application 江西科技师范大学 2019-08-20 CN disclosed
WO-2010082601-A1 NOVEL 2,5-DISUBSTITUTED PYRROLE DERIVATIVE 第一三共株式会社 (JP) 2010-07-22 WO disclosed
US-20090325041-A1 Lithium Secondary Battery HITACHI, LTD. (JP) 2009-12-31 US disclosed
WO-2005000806-A2 LIGANDS FOR NICOTINIC ACETYLCHOLINE RECEPTORS, AND METHODS OF MAKING AND USING THEM GEORGETOWN UNIVERSITY (US) 2005-01-06 WO disclosed
WO-2004099373-A2 BIOCOMPATIBLE RESISTS UNIVERSITY OF NORTH CAROLINA AT CHARLOTTE (US) 2004-11-18 WO disclosed
EP-1351684-A2 COMPOUNDS AND METHODS FOR PROMOTING SMOKING CESSATION Research Triangle Institute (US) 2003-10-15 EP disclosed
WO-2002037927-A2 COMPOUNDS AND METHODS FOR PROMOTING SMOKING CESSATION RESEARCH TRIANGLE INSTITUTE (US) 2002-05-16 WO disclosed
US-6384228-B2 EPIBATIDINE; ANALGESICS; ANIMAL EXTRACTS NIHON MEDI-PHYSICS CO., LTD. (JP) 2002-05-07 US disclosed
US-20020010339-A1 METHOD FOR SYNTHESIS OF HALOPYRIDYL-ACYCLOPENTANE DERIVATIVE AND INTERMEDIATE THEREOF NIHON MEDI-PHYSICS CO., LTD. (JP) 2002-01-24 US disclosed
EP-0267794-B1 PROCESS FOR PREPARING POLYOLEFINS Nippon Petrochemicals Co., Ltd. (JP) 1993-05-05 EP disclosed
EP-0267794-A2 Process for preparing polyolefins Nippon Petrochemicals Co., Ltd. (JP) 1988-05-18 EP disclosed
US-4525555-A TITANIUM COMPOUND SUPPORTED ON SOLID REACTION PRODUCT OF MAGNESIUM HALIDE, SILOXANES, ORGANIC COMPOUNDS NIPPON OIL COMPANY, LIMITED (JP) 1985-06-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020010339-A1 METHOD FOR SYNTHESIS OF HALOPYRIDYL-ACYCLOPENTANE DERIVATIVE AND INTERMEDIATE THEREOF DHPS, ALAD, HAAO MMP2 4472/4885MMP1 4288/4885MMP9 4332/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.