Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | PLK4 | O00444 | 2/20 | 0.32 |
| ▸ | AURKA | O14965 | 2/20 | 0.32 |
| ▸ | DAPK3 | O43293 | 2/20 | 0.32 |
| ▸ | CDK1 | P06493 | 2/20 | 0.32 |
| ▸ | PIM1 | P11309 | 2/20 | 0.32 |
| ▸ | CDK2 | P24941 | 2/20 | 0.32 |
| ▸ | SYK | P43405 | 2/20 | 0.32 |
| ▸ | CLK2 | P49760 | 2/20 | 0.32 |
| ▸ | GSK3A | P49840 | 2/20 | 0.32 |
| ▸ | GSK3B | P49841 | 2/20 | 0.32 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.32 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.32 |
| ▸ | CAMK2B | Q13554 | 2/20 | 0.32 |
| ▸ | CAMK2G | Q13555 | 2/20 | 0.32 |
| ▸ | CAMK2D | Q13557 | 2/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.32 |
| ▸ | TAOK1 | Q7L7X3 | 2/20 | 0.32 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.32 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL436403 | 0.86 | POLB (0.38) | DYRK1AMEN1MAPTKMT2ALMNA | |
| SCHEMBL439672 | 0.86 | DYRK1A (0.35) | PLK4AURKADAPK3CDK1PIM1 | |
| SCHEMBL437482 | 0.84 | CYP3A4 (0.35) | CYP3A4MEN1MAPTKMT2ALMNA | |
| SCHEMBL438319 | 0.80 | NQO2 (0.36) | DYRK1AMEN1MAPTKMT2ALMNA | |
| SCHEMBL436692 | 0.75 | POLB (0.38) | CYP3A4DYRK1AMEN1MAPTKMT2A | |
| SCHEMBL442158 | 0.75 | HAVCR2 (0.54) | MEN1MAPTKMT2ALMNAKDM4E | |
| SCHEMBL440009 | 0.73 | HAVCR2 (0.38) | MEN1MAPTKMT2A | |
| SCHEMBL436999 | 0.73 | NQO2 (0.36) | DYRK1AMEN1MAPTKMT2ALMNA | |
| SCHEMBL21979409 | 0.70 | CCR1 (0.36) | CYP3A4PLK4AURKADAPK3CDK1 | |
| SCHEMBL29671106 | 0.70 | CCR1 (0.36) | CYP3A4PLK4AURKADAPK3CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |