Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.38 |
| ▸ | CCR1 | P32246 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.36 |
| ▸ | CCR8 | P51685 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL436942 | 0.84 | HAVCR2 (0.41) | HAVCR2PDPK1CCR1CCR5CCR8 | |
| SCHEMBL439739 | 0.84 | CCR1 (0.39) | HAVCR2CCR1CCR5CCR8MEN1 | |
| SCHEMBL437599 | 0.83 | CCR1 (0.42) | HAVCR2CCR1CCR5CCR8MEN1 | |
| SCHEMBL439423 | 0.83 | HAVCR2 (0.36) | HAVCR2MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL441974 | 0.80 | HAVCR2 (0.38) | HAVCR2PDPK1CCR1CCR5CCR8 | |
| SCHEMBL437260 | 0.76 | HAVCR2 (0.67) | HAVCR2PKMMEN1KMT2AMAPT | |
| SCHEMBL441951 | 0.76 | HAVCR2 (0.58) | HAVCR2MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL436747 | 0.73 | CYP3A4 (0.32) | MEN1KMT2AMAPT | |
| SCHEMBL436601 | 0.73 | KMT2A (0.33) | HAVCR2MEN1KMT2AALDH1A1 | |
| SCHEMBL441701 | 0.72 | ALDH1A1 (0.43) | HAVCR2PDPK1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |