Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | CCR1 | P32246 | 1/20 | 0.31 |
| ▸ | CCR5 | P51681 | 1/20 | 0.31 |
| ▸ | CCR8 | P51685 | 1/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL436692 | 0.91 | POLB (0.38) | CYP3A4MAPTMEN1KMT2ALMNA | |
| SCHEMBL436747 | 0.84 | CYP3A4 (0.32) | CYP3A4MAPTMEN1KMT2ALMNA | |
| SCHEMBL437555 | 0.84 | HAVCR2 (0.38) | CYP3A4HAVCR2 | |
| SCHEMBL442158 | 0.79 | HAVCR2 (0.54) | MAPTMEN1KMT2ALMNAKDM4E | |
| SCHEMBL439519 | 0.77 | DYRK1A (0.39) | MAPTMEN1KMT2AKDM4EPOLB | |
| SCHEMBL440196 | 0.74 | NPC1 (0.52) | MAPTMEN1KMT2ALMNAKDM4E | |
| SCHEMBL442075 | 0.73 | HAVCR2 (0.46) | MAPTMEN1KMT2ALMNAKDM4E | |
| SCHEMBL437847 | 0.73 | CCR1 (0.42) | CYP3A4MAPTKMT2ALMNAKDM4E | |
| SCHEMBL15146338 | 0.71 | CCR1 (0.45) | CYP3A4MAPTMEN1KMT2ALMNA | |
| SCHEMBL436942 | 0.70 | HAVCR2 (0.41) | MAPTMEN1KMT2ACCR1CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |