Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.32 |
| ▸ | BTK | Q06187 | 1/20 | 0.32 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.31 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL442157 | 0.74 | HAVCR2 (0.36) | HAVCR2DYRK1A | |
| SCHEMBL441422 | 0.74 | HAVCR2 (0.46) | HAVCR2 | |
| SCHEMBL437555 | 0.74 | HAVCR2 (0.38) | HAVCR2DYRK1A | |
| SCHEMBL436994 | 0.72 | HAVCR2 (0.48) | HAVCR2BTK | |
| SCHEMBL19989867 | 0.69 | HCRTR1 (0.36) | EPHB4 | |
| SCHEMBL436692 | 0.69 | POLB (0.38) | HAVCR2MAPK1DYRK1A | |
| SCHEMBL437482 | 0.68 | CYP3A4 (0.35) | HAVCR2 | |
| SCHEMBL440416 | 0.67 | CDK8 (0.33) | HAVCR2 | |
| SCHEMBL437520 | 0.67 | AAK1 (0.34) | — | |
| SCHEMBL3209981 | 0.65 | ALDH1A1 (0.38) | MAPK1DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |