Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR4 | O95977 | 10/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HTR1B | P28222 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1623536 | 0.98 | S1PR4 (0.55) | S1PR4KDM4EHTR1BRAB9ANPC1 | |
| SCHEMBL13947096 | 0.82 | S1PR4 (0.58) | S1PR4KDM4ERAB9ANPC1SMN1; SMN2 | |
| SCHEMBL23600775 | 0.81 | S1PR4 (0.57) | S1PR4KDM4ERAB9ANPC1SMN1; SMN2 | |
| SCHEMBL2127198 | 0.81 | S1PR4 (0.57) | S1PR4KDM4ERAB9ANPC1SMN1; SMN2 | |
| SCHEMBL3933432 | 0.80 | S1PR4 (0.46) | S1PR4RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL14173619 | 0.78 | S1PR4 (0.54) | S1PR4KDM4EHTR1BCYP2C19 | |
| SCHEMBL14290550 | 0.78 | S1PR4 (0.53) | S1PR4KDM4ERAB9ANPC1SMN1; SMN2 | |
| SCHEMBL17815734 | 0.75 | S1PR4 (0.55) | S1PR4KDM4ERAB9ANPC1SMN1; SMN2 | |
| SCHEMBL29444437 | 0.74 | S1PR4 (0.50) | S1PR4KDM4ERAB9ANPC1SMN1; SMN2 | |
| SCHEMBL20124609 | 0.74 | S1PR4 (0.50) | S1PR4KDM4ERAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090291983-A1 | 3-Oxoisoindoline-1-Carboxamide Derivatives as Analgesic Agents | ASTRAZENECA AB (SE) | 2009-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090291983-A1 | 3-Oxoisoindoline-1-Carboxamide Derivatives as Analgesic Agents | OPRD1, OPRK1, OPRM1 | S1PR4 2280/4885KDM4E 2133/4885HTR1B 112/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.