Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | NQO1 | P15559 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9098138 | 0.86 | MAPT (0.50) | MAPTNQO1HPGDKDM4EMEN1 | |
| SCHEMBL4069376 | 0.82 | ALOX5 (0.45) | MAPTHPGDKDM4ERAB9AALDH1A1 | |
| SCHEMBL30380487 | 0.81 | MAPT (0.67) | MAPTNQO1HPGDKDM4EMEN1 | |
| SCHEMBL278576 | 0.81 | MAPT (0.67) | MAPTNQO1HPGDKDM4EMEN1 | |
| Formaldehyde SCHEMBL28780252 | 0.80 | MAPT (0.60) | MAPTNQO1HPGDKDM4EMEN1 | |
| SCHEMBL25986546 | 0.80 | MAPT (0.64) | MAPTNQO1HPGDKDM4EMEN1 | |
| Ammonia Solution, Strong SCHEMBL11476305 | 0.80 | MAPT (0.64) | MAPTNQO1HPGDKDM4EMEN1 | |
| SCHEMBL2497894 | 0.79 | TSHR (0.48) | MAPTHPGDKMT2ARAB9AALDH1A1 | |
| Cyanide SCHEMBL29227829 | 0.77 | MAPT (0.60) | MAPTNQO1HPGDKDM4EMEN1 | |
| SCHEMBL27456613 | 0.76 | MAPT (0.55) | MAPTNQO1HPGDKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7619003-B2 | Process for producing optically active compound | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2009-11-17 | — | — | US | disclosed |
| US-20060173210-A1 | Process for producing optically active compound | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2006-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060173210-A1 | Process for producing optically active compound | ADH5, ADH1A, ADH4 | MAPT 3914/4885NQO1 194/4885HPGD 662/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.