SCHEMBL4370708

SCHEMBL4370708

CCCCCCCCCCCCCCCCCCCCOC(=O)OC[C@H](CO)OC(=O)OCCCCCCCCCCCCCCCCCCCC

nearest known ligand 0.58

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PRKCA P17252 5/20 0.56
PRKCE Q02156 2/20 0.56
PRKCQ Q04759 2/20 0.56
PRKCD Q05655 2/20 0.56
MAPT P10636 1/20 0.47
MAPK1 P28482 1/20 0.47
ALDH1A1 P00352 1/20 0.45
LMNA P02545 1/20 0.45
NAAA Q02083 1/20 0.44
AKT1 P31749 1/20 0.42
EPHX1 P07099 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10941828 0.89 USP2 (0.51) PRKCAPRKCEPRKCQPRKCDMAPT
SCHEMBL10943913 0.86 USP2 (0.56) PRKCAPRKCEPRKCQPRKCDMAPT
SCHEMBL10939817 0.83 PRKCA (0.49) PRKCAPRKCEPRKCQPRKCDMAPT
SCHEMBL10940945 0.83 USP2 (0.51) PRKCAPRKCEPRKCQPRKCDMAPT
SCHEMBL1471715 0.82 NAAA (0.46) PRKCAPRKCEPRKCQPRKCDMAPT
SCHEMBL14891362 0.81 ALDH1A1 (0.44) PRKCAPRKCEPRKCQPRKCDALDH1A1
SCHEMBL18388402 0.81 NAAA (0.52) ALDH1A1LMNANAAAEPHX1
SCHEMBL4419061 0.80 NAAA (0.47) MAPTALDH1A1LMNANAAAEPHX1
SCHEMBL14890980 0.80 ALDH1A1 (0.42) PRKCAPRKCEPRKCQPRKCDALDH1A1
SCHEMBL13133067 0.80 NAAA (0.47) MAPTALDH1A1LMNANAAAEPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2119455-A1 Tripartite raftophilic structures and their use Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2009-11-18 EP disclosed
EP-1732612-B1 TRIPARTITE CONJUGATES CONTAINING A STRUCTURE INTERACTING WITH CELL MEMBRANE RAFTS AND THEIR USE JADO TECHNOLOGIES GMBH (DE) 2009-09-16 EP disclosed
US-20080317767-A1 Tripartitle Raftophilic Strutures and their Use MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) 2008-12-25 US disclosed
EP-1732612-A1 TRIPARTITE CONJUGATES CONTAINING A STRUCTURE INTERACTING WITH CELL MEMBRANE RAFTS AND THEIR USE Jadolabs Gmbh (DE) 2006-12-20 EP disclosed
WO-2005097199-A1 TRIPARTITE CONJUGATES CONTAINING A STRUCTURE INTERACTING WITH CELL MEMBRANE RAFTS AND THEIR USE JADOLABS GMBH (DE) 2005-10-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080317767-A1 Tripartitle Raftophilic Strutures and their Use FGB, CLTB, CD38 PRKCA 3580/4885PRKCE 3460/4885PRKCQ 2989/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.