Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 5/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 5/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 5/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 5/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 5/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 5/20 | 0.34 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.34 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.34 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.33 |
| ▸ | ADK | P55263 | 2/20 | 0.33 |
| ▸ | OGA | O60502 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 4/20 | 0.32 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL483990 | 0.81 | GABRA1 (0.37) | FFAR1GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL17038144 | 0.81 | GABRA5 (0.44) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL4374387 | 0.80 | FGFR4 (0.43) | FFAR1GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL7604375 | 0.74 | P4HTM (0.47) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL4034638 | 0.73 | JAK2 (0.40) | OGAUSP30 | |
| SCHEMBL30223758 | 0.72 | FFAR1 (0.69) | FFAR1 | |
| SCHEMBL2806910 | 0.71 | RAB9A (0.44) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL4370752 | 0.71 | FFAR1 (0.43) | FFAR1GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL15173773 | 0.70 | HCAR3 (0.38) | HCAR3 | |
| SCHEMBL2099047 | 0.70 | GBA1 (0.50) | HCAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009117421-A2 | HETEROCYCLIC MODULATORS OF GPR119 FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2009-09-24 | — | — | WO | disclosed |