Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR4 | P22455 | 1/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.36 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4370754 | 0.80 | FFAR1 (0.35) | USP30HCAR3FFAR1GRM5GABRA1 | |
| SCHEMBL15378607 | 0.80 | FGFR4 (0.36) | FGFR4HCAR3EGLN1JAK2JAK3 | |
| SCHEMBL15950272 | 0.79 | GABRG2 (0.41) | FGFR4USP30JAK2JAK3GRM5 | |
| SCHEMBL2545907 | 0.78 | ADK (0.40) | FGFR4JAK2JAK3GRM5 | |
| SCHEMBL25382866 | 0.75 | KDM4E (0.34) | FGFR4HCAR3 | |
| SCHEMBL2099047 | 0.74 | GBA1 (0.50) | HCAR3MEN1KMT2A | |
| SCHEMBL15173773 | 0.74 | HCAR3 (0.38) | HCAR3JAK2MEN1KMT2A | |
| SCHEMBL477388 | 0.74 | HCAR3 (0.38) | USP30HCAR3MEN1KMT2ACA12 | |
| SCHEMBL691857 | 0.71 | HCAR3 (0.46) | USP30HCAR3MEN1KMT2AGABRA1 | |
| SCHEMBL3463002 | 0.71 | USP30 (0.53) | USP30MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023163033-A1 | NOVEL COMPOUND, α-SYNUCLEIN AGGREGATE BINDER, AND USE THEREOF | 国立研究開発法人量子科学技術研究開発機構 | 2023-08-31 | — | — | WO | disclosed |
| WO-2009117421-A2 | HETEROCYCLIC MODULATORS OF GPR119 FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2009-09-24 | — | — | WO | disclosed |