SCHEMBL4371622

SCHEMBL4371622

CC1(C(=O)O)C=CC(c2ccccc2)=CC1

nearest known ligand 0.33

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
RARA P10276 2/20 0.33
RARB P10826 2/20 0.33
RARG P13631 2/20 0.33
RXRA P19793 1/20 0.33
NR2E1 Q9Y466 1/20 0.33
MAPK1 P28482 1/20 0.33
MAPT P10636 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
CCR2 P41597 1/20 0.31
THRB P10828 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
KDM4E B2RXH2 1/20 0.31
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 1/20 0.31
KMT2A Q03164 1/20 0.31
LMNA P02545 1/20 0.30
AKR1C1 Q04828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28908500 0.94 RARA (0.31) RARARARBRARGRXRANR2E1
SCHEMBL28768953 0.90 RARA (0.33) RARARARBRARGRXRANR2E1
SCHEMBL6135814 0.87 HSD17B1 (0.33) RARARARBRARGMAPTSMN1; SMN2
SCHEMBL5320073 0.86 LMNA (0.36) RARARARBRARGRXRANR2E1
SCHEMBL19746580 0.86 MEN1 (0.42) MAPTSMN1; SMN2KDM4EMEN1ALDH1A1
Hydrogen Sulfide SCHEMBL27540779 0.84 LMNA (0.36) RARARARBRARGRXRANR2E1
SCHEMBL18601442 0.83 MAOB (0.36) RARARARBRARGRXRANR2E1
Sulfurous Acid SCHEMBL27760712 0.82 LMNA (0.34) RARARARBRARGRXRANR2E1
SCHEMBL8501575 0.82 FFAR1 (0.37) MAPTSMN1; SMN2TDP1KDM4EMEN1
SCHEMBL28757628 0.82 TSHR (0.41) SMN1; SMN2MEN1ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115433204-B Synthesis method and application of spiro-expandable monomer with multi-benzene ring structure 深圳市安伯斯科技有限公司 2024-01-19 CN claimed
CN-115433204-A Synthetic method and application of spiro-expansible monomer with multi-benzene ring structure 深圳市安伯斯科技有限公司 2022-12-06 CN claimed
CN-114641291-A Compositions of small molecule therapeutic compounds 戴尔普尔有限公司 2022-06-17 CN claimed
CN-112004538-A Compositions of small molecule therapeutic compounds 德尔宝股份有限公司 2020-11-27 CN claimed
CN-109890365-A The composition of small molecule therapy immunomodulator compounds 戴尔普尔有限公司 2019-06-14 CN claimed
CN-115433204-B Synthesis method and application of spiro-expandable monomer with multi-benzene ring structure 深圳市安伯斯科技有限公司 2024-01-19 CN disclosed
CN-115433204-B Synthesis method and application of spiro-expandable monomer with multi-benzene ring structure 深圳市安伯斯科技有限公司 2024-01-19 CN disclosed
CN-115433204-A Synthetic method and application of spiro-expansible monomer with multi-benzene ring structure 深圳市安伯斯科技有限公司 2022-12-06 CN disclosed
CN-115433204-A Synthetic method and application of spiro-expansible monomer with multi-benzene ring structure 深圳市安伯斯科技有限公司 2022-12-06 CN disclosed
CN-114641291-A Compositions of small molecule therapeutic compounds 戴尔普尔有限公司 2022-06-17 CN disclosed
CN-112004538-A Compositions of small molecule therapeutic compounds 德尔宝股份有限公司 2020-11-27 CN disclosed
CN-109890365-A The composition of small molecule therapy immunomodulator compounds 戴尔普尔有限公司 2019-06-14 CN disclosed
CN-103657631-A Catalyst and method for producing carboxylic acid and/or carboxylic anhydride in the presence of the catalyst MITSUBISHI GAS CHEMICAL CO 2014-03-26 CN disclosed
CN-101632925-B Catalyst and process for producing carboxylic acid and/or carboxylic acid anhydride using the same MITSUBISHI GAS CHEMICAL CO 2014-02-26 CN disclosed
CN-101090977-B Tripeptide and tetrapeptide thioethers TELIK INC 2013-04-10 CN disclosed
CN-102574786-A Dihydroorotate dehydrogenase inhibitors MERCK SERONO SA 2012-07-11 CN disclosed
CN-101632925-A Catalyst and process for producing carboxylic acid and/or carboxylic acid anhydride using the same MITSUBISHI GAS CHEMICAL CO 2010-01-27 CN disclosed
WO-2009137322-A2 PROCESSES FOR THE PREPARATION OF BIPHENYL COMPOUNDS THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2009-11-12 WO disclosed
CN-101090977-A Tripeptide and tetrapeptide thioethers TELIK INC (US) 2007-12-19 CN disclosed
CN-1104204-A Recovery of 4,4'-biphenyldicarbonacid-dimethylester HOECHST AG (DE) 1995-06-28 CN disclosed