Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 1/20 | 0.33 |
| ▸ | RARA | P10276 | 1/20 | 0.33 |
| ▸ | RARB | P10826 | 1/20 | 0.33 |
| ▸ | RARG | P13631 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4371622 | 0.87 | RARA (0.33) | RARARARBRARGMEN1LMNA | |
| SCHEMBL3884549 | 0.82 | GRIN2B (0.32) | MEN1MAPTKMT2A | |
| SCHEMBL28908500 | 0.82 | RARA (0.31) | RARARARBRARG | |
| SCHEMBL31559989 | 0.78 | APP (0.34) | HSD17B1MEN1LMNAMAPTRAB9A | |
| SCHEMBL28768953 | 0.78 | RARA (0.33) | RARARARBRARGLMNAMAPT | |
| SCHEMBL5320073 | 0.74 | LMNA (0.36) | RARARARBRARGMEN1LMNA | |
| SCHEMBL19746580 | 0.74 | MEN1 (0.42) | MEN1MAPTKMT2ACYP2C19CYP2C9 | |
| SCHEMBL11581494 | 0.73 | ESR1 (0.37) | MEN1LMNAMAPTRAB9AKMT2A | |
| SCHEMBL3883554 | 0.73 | ALDH1A1 (0.33) | HSD17B1RARARARBRARGMEN1 | |
| SCHEMBL6135426 | 0.72 | GRIN2B (0.35) | MEN1MAPTRAB9AKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1430025-A4 | METHODS AND COMPOSITIONS FOR TREATING OR PREVENTING BACTERIAL INFECTION | ZHU DEXU (CN) | 2005-04-27 | — | — | EP | disclosed |
| EP-1430025-A1 | METHODS AND COMPOSITIONS FOR TREATING OR PREVENTING BACTERIAL INFECTION | Zhu, Dexu (CN) | 2004-06-23 | — | — | EP | disclosed |
| US-6734212-B2 | ADMINISTERING AGENT THAT SELECTIVELY INHIBITS BACTERIAL DNA REPLICATION INITIATION; FOR DISEASE OR DISORDER CAUSED BY OR ASSOCIATED WITH E. COLI OR H. PYLORI INFECTION | SHANGHAI EAST BEST BIOPHARMACEUTICAL (CN) | 2004-05-11 | — | — | US | disclosed |
| US-20030125384-A1 | Methods and compositions for treating or preventing bacterial infection | NANJING UNIVERSITY (CN) | 2003-07-03 | — | — | US | disclosed |
| WO-2003029201-A1 | METHODS AND COMPOSITIONS FOR TREATING OR PREVENTING BACTERIAL INFECTION | ZHU DEXU (CN) | 2003-04-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030125384-A1 | Methods and compositions for treating or preventing bacterial infection | MPO, TNF, APC | HSD17B1 1368/4885RARA 821/4885RARB 947/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.