Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ILK | Q13418 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.36 |
| ▸ | TUBB | P07437 | 1/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.36 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL441437 | 0.88 | MAPT (0.57) | MAPTNR4A2HSP90AA1NPC1HSP90AB1 | |
| SCHEMBL439448 | 0.83 | NR4A2 (0.59) | MAPTNR4A2HSP90AA1HSP90AB1CRHR1 | |
| SCHEMBL441438 | 0.79 | MAPT (0.43) | MAPTHSP90AA1NPC1HSP90AB1GAA | |
| SCHEMBL17502192 | 0.74 | MAPT (0.60) | MAPTNR4A2HSP90AA1NPC1RAB9A | |
| SCHEMBL437233 | 0.73 | NR4A2 (0.51) | MAPTNR4A2HSP90AA1HSP90AB1RAB9A | |
| SCHEMBL11543194 | 0.73 | NR4A2 (0.51) | MAPTNR4A2RAB9ACRHR1GAA | |
| SCHEMBL439805 | 0.73 | NR4A2 (0.47) | MAPTNR4A2HSP90AA1NPC1HSP90AB1 | |
| SCHEMBL10251084 | 0.71 | DCPS (0.57) | MAPTHSP90AA1NPC1RAB9AALDH1A1 | |
| SCHEMBL4176630 | 0.70 | PDE4A (0.47) | MAPTNR4A2NPC1RAB9ACRHR1 | |
| Hydrochloric Acid SCHEMBL16716886 | 0.69 | PDE4A (0.46) | MAPTNR4A2NPC1RAB9ACRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |