SCHEMBL4373436

SCHEMBL4373436

Cc1sccccc(Cl)c(C)c1C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.40
LMNA P02545 5/20 0.38
TSHR P16473 3/20 0.38
HPGD P15428 3/20 0.35
SMN1; SMN2 Q16637 3/20 0.35
ALOX12 P18054 2/20 0.35
GAA P10253 2/20 0.33
POLB P06746 1/20 0.33
KCNN4 O15554 1/20 0.32
MAPT P10636 4/20 0.32
THRB P10828 1/20 0.32
KMT2A Q03164 3/20 0.32
L3MBTL1 Q9Y468 2/20 0.32
KDM4E B2RXH2 2/20 0.32
MEN1 O00255 2/20 0.32
TP53 P04637 1/20 0.32
ALOX15 P16050 1/20 0.32
MAPK1 P28482 1/20 0.32
HSD17B10 Q99714 1/20 0.32
NPC1 O15118 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL154107 0.91 ALDH1A1 (0.40) ALDH1A1LMNATSHRHPGDSMN1; SMN2
SCHEMBL4369368 0.91 ALDH1A1 (0.40) ALDH1A1LMNATSHRHPGDSMN1; SMN2
Water SCHEMBL3327760 0.89 ALDH1A1 (0.39) ALDH1A1LMNATSHRHPGDSMN1; SMN2
SCHEMBL150091 0.82 TSHR (0.41) ALDH1A1LMNATSHRHPGDSMN1; SMN2
SCHEMBL752673 0.77 TSHR (0.41) ALDH1A1TSHRHPGDSMN1; SMN2ALOX12
Hydrochloric Acid SCHEMBL31150435 0.76 TSHR (0.39) ALDH1A1TSHRHPGDSMN1; SMN2ALOX12
Hydrochloric Acid SCHEMBL154108 0.76 TSHR (0.39) ALDH1A1TSHRHPGDSMN1; SMN2ALOX12
Water SCHEMBL5196978 0.76 TSHR (0.39) ALDH1A1TSHRHPGDSMN1; SMN2ALOX12
Hydrochloric Acid SCHEMBL3327763 0.74 TSHR (0.38) ALDH1A1TSHRHPGDSMN1; SMN2ALOX12
SCHEMBL753567 0.73 TSHR (0.41) ALDH1A1LMNATSHRHPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2046767-B1 PROCESS FOR PREPARING DIAMINOPHENOTHIAZINIUM COMPOUNDS PROVENCE TECHNOLOGIES (FR) 2015-04-22 EP claimed
US-8765942-B2 Process for preparing diaminophenothiazinium compounds PROVENCE TECHNOLOGIES (FR) 2014-07-01 US claimed
US-20090291943-A1 PROCESS FOR PREPARING DIAMINOPHENOTHIAZINIUM COMPOUNDS PROVEPHARM LIFE SOLUTIONS (FR) 2009-11-26 US claimed
US-12442029-B2 Method and system for imaging a blood sample S.D. SIGHT DIAGNOSTICS LTD. (IL) 2025-10-14 US disclosed
US-20220390734-A1 METHOD AND SYSTEM FOR IMAGING A BLOOD SAMPLE S.D. SIGHT DIAGNOSTICS LTD. (IL) 2022-12-08 US disclosed
US-11434515-B2 Method and system for imaging a blood sample S.D. SIGHT DIAGNOSTICS LTD. (IL) 2022-09-06 US disclosed
CN-109342155-B Method, kit and system for imaging a blood sample 思迪赛特诊断有限公司 2022-05-31 CN disclosed
US-20190002950-A1 METHOD AND SYSTEM FOR IMAGING A BLOOD SAMPLE S.D. SIGHT DIAGNOSTICS LTD. (IL) 2019-01-03 US disclosed
US-10093957-B2 Method, kit and system for imaging a blood sample S.D. SIGHT DIAGNOSTICS LTD. (IL) 2018-10-09 US disclosed
US-10087153-B2 Method of preparing diaminophenothiazinium Curadel, LLC (US) 2018-10-02 US disclosed
US-20170183320-A1 METHOD OF PREPARING DIAMINOPHENOTHIAZINIUM NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2017-06-29 US disclosed
US-9329129-B2 Method, kit and system for imaging a blood sample S.D. SIGHT DIAGNOSTICS LTD. (IL) 2016-05-03 US disclosed
US-9227945-B2 Process for preparing diaminophenothiazinium compounds PROVENCE TECHNOLOGIES (FR) 2016-01-05 US disclosed
US-20150316477-A1 METHOD, KIT AND SYSTEM FOR IMAGING A BLOOD SAMPLE S.D. SIGHT DIAGNOSTICS LTD. (IL) 2015-11-05 US disclosed
WO-2015001553-A1 A METHOD, KIT AND SYSTEM FOR IMAGING A BLOOD SAMPLE SIGHT DIAGNOSTICS LTD. (IL) 2015-01-08 WO disclosed
US-8815850-B2 Process for preparing diaminophenothiazinium compounds PROVENCE TECHNOLOGIES (FR) 2014-08-26 US disclosed
US-20140235854-A1 Process for Preparing Diaminophenothiazinium Compounds PROVENCE TECHNOLOGIES (FR) 2014-08-21 US disclosed
US-8765942-B2 Process for preparing diaminophenothiazinium compounds PROVENCE TECHNOLOGIES (FR) 2014-07-01 US disclosed
US-20130005713-A1 Process for Preparing Diaminophenothiazinium Compounds PROVENCE TECHNOLOGIES (FR) 2013-01-03 US disclosed
US-20090291943-A1 PROCESS FOR PREPARING DIAMINOPHENOTHIAZINIUM COMPOUNDS PROVEPHARM LIFE SOLUTIONS (FR) 2009-11-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10087153-B2 Method of preparing diaminophenothiazinium NEFM, DDT, DUS2 ALDH1A1 1545/4885LMNA 3942/4885TSHR 2678/4885
US-20090291943-A1 PROCESS FOR PREPARING DIAMINOPHENOTHIAZINIUM COMPOUNDS DCPS, QDPR, DNPEP ALDH1A1 1379/4885LMNA 2709/4885TSHR 3603/4885
US-20140235854-A1 Process for Preparing Diaminophenothiazinium Compounds DRD4, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, C5 ALDH1A1 3072/4885LMNA 2165/4885TSHR 368/4885
US-20130005713-A1 Process for Preparing Diaminophenothiazinium Compounds DCPS, QDPR, DNPEP ALDH1A1 1412/4885LMNA 2815/4885TSHR 3711/4885
US-20170183320-A1 METHOD OF PREPARING DIAMINOPHENOTHIAZINIUM NEFM, DDT, DUS2 ALDH1A1 1545/4885LMNA 3942/4885TSHR 2678/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.