SCHEMBL150091

SCHEMBL150091

Cc1sccccccc1Cl

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.41
LMNA P02545 3/20 0.41
CYP2A6 P11509 1/20 0.36
KCNN4 O15554 1/20 0.34
ALDH1A1 P00352 6/20 0.33
ALOX12 P18054 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
KDM4E B2RXH2 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
KMT2A Q03164 2/20 0.33
HSD11B1 P28845 2/20 0.33
ACHE P22303 1/20 0.33
TP53 P04637 1/20 0.33
MEN1 O00255 1/20 0.33
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33
HPGD P15428 1/20 0.33
ALOX15 P16050 1/20 0.33
MAPK1 P28482 1/20 0.33
HSD17B10 Q99714 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4369368 0.86 ALDH1A1 (0.40) TSHRLMNACYP2A6KCNN4ALDH1A1
SCHEMBL4373436 0.82 ALDH1A1 (0.40) TSHRLMNAKCNN4ALDH1A1ALOX12
SCHEMBL434410 0.79
SCHEMBL28919218 0.75 TSHR (0.45) TSHRLMNACYP2A6KCNN4ALDH1A1
SCHEMBL752807 0.75 ACHE (0.45) TSHRLMNACYP2A6ALDH1A1ALOX12
SCHEMBL29908244 0.75 TSHR (0.45) TSHRLMNACYP2A6KCNN4ALDH1A1
Hydrochloric Acid SCHEMBL4369366 0.73 ACHE (0.43) TSHRLMNACYP2A6ALDH1A1ALOX12
SCHEMBL154107 0.73 ALDH1A1 (0.40) TSHRLMNAALDH1A1ALOX12L3MBTL1
SCHEMBL753567 0.71 TSHR (0.41) TSHRLMNACYP2A6ALDH1A1ALOX12
SCHEMBL3626521 0.71 TSHR (0.41) TSHRLMNACYP2A6ALDH1A1ALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 227 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3698140-A1 METHODS FOR MONITORING BLADDER CANCER IMMUNOTHERAPY NantBio, Inc. (US) 2020-08-26 EP claimed
WO-2019079009-A1 METHODS FOR MONITORING BLADDER CANCER IMMUNOTHERAPY NANTBIO, INC. (US) 2019-04-25 WO claimed
US-20190117153-A1 METHODS FOR MONITORING BLADDER CANCER IMMUNOTHERAPY NANTBIO, INC. 2019-04-25 US claimed
EP-2046767-B1 PROCESS FOR PREPARING DIAMINOPHENOTHIAZINIUM COMPOUNDS PROVENCE TECHNOLOGIES (FR) 2015-04-22 EP claimed
US-8765942-B2 Process for preparing diaminophenothiazinium compounds PROVENCE TECHNOLOGIES (FR) 2014-07-01 US claimed
US-20140123718-A1 LIQUID PHOSPHATE FERTILIZER SOLUTION FOR AGRONOMIC USE ANTELO JOSÉ RAMÓN FLORENCIO (AR) 2014-05-08 US claimed
WO-2012012656-A2 MATERIALS AND METHODS FOR TREATING NEURODEGENERATIVE DISEASES UNIVERSITY OF SOUTH FLORIDA (US) 2012-01-26 WO claimed
US-20090291943-A1 PROCESS FOR PREPARING DIAMINOPHENOTHIAZINIUM COMPOUNDS PROVEPHARM LIFE SOLUTIONS (FR) 2009-11-26 US claimed
US-4361561-A METHYLENE BLUE Naylor, Graham John (GB) 1982-11-30 US claimed
US-12576140-B2 Cyclophilin 40 for reduction of neurotoxic fibrils and treatment of neurodegenerative diseases UNIVERSITY OF SOUTH FLORIDA (US) 2026-03-17 US disclosed
EP-4017496-B1 FORMULATIONS FOR USE IN THE PREVENTION AND/OR TREATMENT OF PERIPHERAL NEUROPATHY AND ITS ASSOCIATED DISEASES LOH YIN SZE (SG) 2026-01-07 EP disclosed
US-20250367466-A1 LIGHT THERAPY BED WITH ILLUMINATED MESH SUPPORT STRUCTURE POWER MEDICINE LLC (US) 2025-12-04 US disclosed
US-20250332177-A1 Methylene Blue COVID-19 Composition FRIKHA DORRA (US) 2025-10-30 US disclosed
US-20250325557-A1 3, 7-DIAMINO-10H-PHENOTHIAZINE SALTS AND THEIR USE WISTA LABORATORIES LTD. (SG) 2025-10-23 US disclosed
US-5353449-A Toilet training method TINKLE MAGIC, INC. (US) 1994-10-11 US disclosed
US-4548927-A Method and agents for raising animal tolerance to oxidant stress-inducing antibiotics EATON JOHN W (US) 1985-10-22 US disclosed
EP-0144402-A1 METHOD AND AGENTS FOR RAISING ANIMAL TOLERANCE TO OXIDANT STRESS-INDUCING ANTIBIOTICS EATON, John W. (US) 1985-06-19 EP disclosed
WO-1984004679-A1 METHOD AND AGENTS FOR RAISING ANIMAL TOLERANCE TO OXIDANT STRESS-INDUCING ANTIBIOTICS EATON JOHN W 1984-12-06 WO disclosed
US-4414212-A Method of treatment of pre-menstrual syndrome Naylor, Graham J. (GB) 1983-11-08 US disclosed
US-4361561-A METHYLENE BLUE Naylor, Graham John (GB) 1982-11-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250325557-A1 3, 7-DIAMINO-10H-PHENOTHIAZINE SALTS AND THEIR USE PSEN1, PSEN2, APP TSHR 1453/4885LMNA 222/4885CYP2A6 1042/4885
US-12576140-B2 Cyclophilin 40 for reduction of neurotoxic fibrils and treatment of neurodegenerative diseases PSEN1, PSEN2, PRNP TSHR 2889/4885LMNA 383/4885CYP2A6 3521/4885
US-20090291943-A1 PROCESS FOR PREPARING DIAMINOPHENOTHIAZINIUM COMPOUNDS DCPS, QDPR, DNPEP TSHR 3603/4885LMNA 2709/4885CYP2A6 851/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.