Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 3/20 | 0.53 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | P2RX1 | P51575 | 5/20 | 0.38 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.37 |
| ▸ | TMPRSS4 | Q9NRS4 | 2/20 | 0.37 |
| ▸ | IKBKB | O14920 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4376336 | 0.98 | RAPGEF4 (0.51) | RAPGEF4SLC13A3HDAC3HDAC1HDAC2 | |
| SCHEMBL998165 | 0.84 | IDO1 (0.46) | RAPGEF4MAPTALDH1A1P2RX1P2RX4 | |
| Hydrochloric Acid SCHEMBL999258 | 0.82 | IDO1 (0.48) | RAPGEF4MAPTALDH1A1P2RX1P2RX4 | |
| SCHEMBL12706897 | 0.79 | RAPGEF4 (0.57) | RAPGEF4SLC13A3HDAC3HDAC1HDAC2 | |
| SCHEMBL997922 | 0.77 | HDAC3 (0.42) | RAPGEF4HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL321756 | 0.77 | AHR (0.52) | RAPGEF4SLC13A3HDAC3HDAC1HDAC2 | |
| SCHEMBL486657 | 0.77 | IDO1 (0.50) | RAPGEF4MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL3786224 | 0.77 | RAPGEF4 (0.47) | RAPGEF4SLC13A3MEN1KMT2AALDH1A1 | |
| SCHEMBL25112073 | 0.75 | MAPT (0.43) | RAPGEF4MAPTALDH1A1SMN1; SMN2P2RX1 | |
| SCHEMBL11677821 | 0.75 | RAPGEF4 (0.52) | RAPGEF4MAPTALDH1A1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023036217-A1 | ACRYLAMIDE COMPOUND AND USE THEREOF | 南京明德新药研发有限公司 | 2023-03-16 | — | — | WO | disclosed |
| WO-2009117421-A2 | HETEROCYCLIC MODULATORS OF GPR119 FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2009-09-24 | — | — | WO | disclosed |