Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.44 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6227960 | 0.82 | LMNA (0.48) | L3MBTL1TDP1AKR1C1PRMT1ESR1 | |
| SCHEMBL4632474 | 0.82 | LMNA (0.48) | L3MBTL1TDP1AKR1C1PRMT1ESR1 | |
| SCHEMBL8768148 | 0.78 | TDP1 (0.50) | L3MBTL1TDP1ALDH1A1LMNAMAPT | |
| SCHEMBL8528509 | 0.78 | AKR1C1 (0.47) | AKR1C1PRMT1ESR1CYP19A1CYP11B2 | |
| SCHEMBL2835097 | 0.77 | AKR1C1 (0.45) | L3MBTL1AKR1C1PRMT1ESR1CYP19A1 | |
| SCHEMBL146717 | 0.77 | AKR1C1 (0.45) | AKR1C1PRMT1ESR1CYP19A1CYP11B2 | |
| SCHEMBL5960470 | 0.77 | AKR1C1 (0.45) | L3MBTL1AKR1C1PRMT1ESR1CYP19A1 | |
| SCHEMBL10711205 | 0.77 | AKR1C1 (0.45) | AKR1C1PRMT1ESR1CYP19A1CYP11B2 | |
| SCHEMBL28860739 | 0.76 | SRC (0.55) | TDP1AKR1C1PRMT1ALDH1A1LMNA | |
| SCHEMBL10910203 | 0.73 | AKR1C1 (0.52) | L3MBTL1TDP1AKR1C1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2119457-B1 | Method of producing a hyperpolarised contrast agent | GE HEALTHCARE AS (NO) | 2012-10-03 | — | — | EP | disclosed |
| EP-2119457-A1 | Method of magnetic resonance investigation with hyperpolarised contrast agents | GE Healthcare AS (NO) | 2009-11-18 | — | — | EP | disclosed |